I am Heng Wan, holding an MD and PhD, and currently serving as an Associate Professor at the Department of Endocrinology and Metabolism, The Eighth Affiliated Hospital, Southern Medical University, Guangdong, China. My academic journey has been shaped by a consistent focus on understanding and addressing metabolic diseases, with a particular emphasis on uncovering the complex interplay between environmental factors and these conditions. I pursued a Master’s degree in Internal Medicine (Endocrine and metabolic disease) at Southern Medical University from 2011 to 2014, followed by a PhD in the same field at Shanghai Jiao Tong University School of Medicine from 2018 to 2021, which deepened my expertise in endocrinology and metabolic research . My research focuses on identifying risk factors, particularly endocrine environmental disruptors, for metabolic diseases such as diabetes mellitus and its complications, as well as NAFLD/MAFLD through population-based cohort studies (SPECT-China, METAL study, and SPEED-Shunde study). What sets my work apart is the integration of large-scale epidemiological data with molecular mechanisms, allowing me to bridge the gap between population-level observations and individual-level biological processes. For instance, my studies on heavy metal exposure—including lead—have not only demonstrated associations with fatty liver disease and elevated fasting glucose but also explored the underlying pathways, such as gut microbiota variations and hepatic gluconeogenesis, providing a more comprehensive understanding of how environmental factors contribute to metabolic dysfunction . I have achieved significant academic milestones, including being named a Shanghai Outstanding Graduate in 2021 . As the first author or corresponding author, I have published over 30 SCI papers with a cumulative impact factor exceeding 200, and my representative works have appeared in journals such as Journal of Hepatology, Cardiovasc Diabetol, and J Clin Endocrinol Metab. Many of these studies have been cited in subsequent research, reflecting their contribution to advancing the field, and my H-index of 22 further underscores the influence of my work . In addition to my research output, I have actively contributed to academic journals. I served as a reviewer editor for Frontiers in Endocrinology from 2021 to 2022, where I was responsible for evaluating manuscripts, providing constructive feedback, and ensuring the quality of published research in the field of endocrinology . Currently, I hold the position of young editorial board member for Journal of Diabetes, a role that involves participating in editorial decisions, shaping the journal’s scope, and promoting impactful research in diabetes and related metabolic disorders. These experiences have not only enhanced my ability to assess scientific rigor but also deepened my understanding of the broader academic landscape and the needs of researchers in the field. My long-term research goal is to deepen the understanding of the relationship between environmental factors and metabolic diseases, contributing to the development of targeted prevention and treatment strategies. Specifically, I aim to expand my cohort studies to include more diverse populations, exploring how regional environmental differences—such as varying levels of pollution or dietary patterns—affect metabolic health outcomes. I also plan to incorporate advanced technologies, such as metabolomics and metagenomics, to identify novel biomarkers that can predict disease risk or response to interventions, ultimately translating these findings into clinical practice to improve patient care. Professionally, I possess a set of skills that enable me to thrive in both research and academic collaboration. My strong communication skills allow me to effectively present complex research findings to diverse audiences, from fellow scientists at conferences to healthcare professionals and students. Interpersonal skills have been crucial in building and maintaining collaborative networks, both within my institution and with researchers from other universities and organizations. Additionally, my problem-solving skills—honed through troubleshooting challenges in data analysis, study design, and manuscript preparation—help me navigate the inevitable obstacles in research. I also take pride in my mentoring abilities, having guided several graduate students and junior researchers in their projects, fostering their growth as independent scientists. Beyond my academic and professional pursuits, I am committed to staying abreast of the latest advancements in endocrinology and metabolism. In my spare time, I regularly read top-tier journals, attend virtual and in-person conferences, and engage in discussions with colleagues to exchange ideas and stay informed about emerging trends. Outside of work, I enjoy outdoor activities such as hiking and running, which not only keep me physically active but also provide mental clarity and inspiration for my research. I also value spending time with my family, as their support has been instrumental in my career development. Looking ahead, I am excited to continue pushing the boundaries of research in metabolic diseases, leveraging my expertise in environmental risk factors and cohort studies to make meaningful contributions to public health. Whether through publishing impactful papers, mentoring the next generation of researchers, or collaborating on interdisciplinary projects, I remain dedicated to advancing our understanding of these complex conditions and improving the lives of those affected by them.