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High Impact Articles
High impact papers are those to which special attention is paid by experts in the given field, with a large number of visitors, frequent downloads and higher citation rates. The research must be creative, with high academic standards and have a wide influence, if it is to become a high impact paper. They are ranked by the number of downloads.
Rank Full Article
1
Cost effectiveness of intensive care in a low resource setting: A prospective cohort of medical critically ill patients  
Hajrunisa Cubro, Rabija Somun-Kapetanovic, Guillaume Thiery, Daniel Talmor, Ognjen Gajic 
World J Crit Care Med 5(2):150-164. Published online May 4, 2016. doi: 10.5492/wjccm.v5.i2.150
2
Cough as a neurological sign: What a clinician should know  
Mohammed Al-Biltagi, Adel Salah Bediwy, Nermin Kamal Saeed 
World J Crit Care Med 11(3):115-128. Published online May 9, 2022. doi: 10.5492/wjccm.v11.i3.115
3
Efficacy of prone position in acute respiratory distress syndrome patients: A pathophysiology-based review  
Vasilios Koulouras, Georgios Papathanakos, Athanasios Papathanasiou, Georgios Nakos 
World J Crit Care Med 5(2):121-136. Published online May 4, 2016. doi: 10.5492/wjccm.v5.i2.121
4
Point of care venous Doppler ultrasound: Exploring the missing piece of bedside hemodynamic assessment  
Pablo Galindo, Carlos Gasca, Eduardo R Argaiz, Abhilash Koratala 
World J Crit Care Med 10(6):310-322. Published online Nov 9, 2021. doi: 10.5492/wjccm.v10.i6.310
5
Focus on peripherally inserted central catheters in critically ill patients  
Paolo Cotogni, Mauro Pittiruti 
World J Crit Care Med 3(4):80-94. Published online Nov 4, 2014. doi: 10.5492/wjccm.v3.i4.80
6
Vitamin C in the critically ill - indications and controversies  
Christoph S Nabzdyk, Edward A Bittner 
World J Crit Care Med 7(5):52-61. Published online Oct 16, 2018. doi: 10.5492/wjccm.v7.i5.52
7
Intravenous vitamin C as adjunctive therapy for enterovirus/rhinovirus induced acute respiratory distress syndrome  
Alpha A Fowler III, Christin Kim, Lawrence Lepler, Rajiv Malhotra, Orlando Debesa, Ramesh Natarajan, Bernard J Fisher, Aamer Syed, Christine DeWilde, Anna Priday, Vigneshwar Kasirajan 
World J Crit Care Med 6(1):85-90. Published online Feb 4, 2017. doi: 10.5492/wjccm.v6.i1.85
8
Prevention of stress-related ulcer bleeding at the intensive care unit: Risks and benefits of stress ulcer prophylaxis  
Lukas Buendgens, Alexander Koch, Frank Tacke 
World J Crit Care Med 5(1):57-64. Published online Feb 4, 2016. doi: 10.5492/wjccm.v5.i1.57
9
Effects of intrapulmonary percussive ventilation on airway mucus clearance: A bench model  
Lorena Fernandez-Restrepo, Lauren Shaffer, Bravein Amalakuhan, Marcos I Restrepo, Jay Peters, Ruben Restrepo 
World J Crit Care Med 6(3):164-171. Published online Aug 4, 2017. doi: 10.5492/wjccm.v6.i3.164
10
Use of venous-to-arterial carbon dioxide tension difference to guide resuscitation therapy in septic shock  
Jihad Mallat, Malcolm Lemyze, Laurent Tronchon, Benoît Vallet, Didier Thevenin 
World J Crit Care Med 5(1):47-56. Published online Feb 4, 2016. doi: 10.5492/wjccm.v5.i1.47
11
Point-of-care ultrasound for critically-ill patients: A mini-review of key diagnostic features and protocols  
Yie Hui Lau, Kay Choong See 
World J Crit Care Med 11(2):70-84. Published online Mar 9, 2022. doi: 10.5492/wjccm.v11.i2.70
12
Plasma-Lyte 148: A clinical review  
Laurence Weinberg, Neil Collins, Kiara Van Mourik, Chong Tan, Rinaldo Bellomo 
World J Crit Care Med 5(4):235-250. Published online Nov 4, 2016. doi: 10.5492/wjccm.v5.i4.235
13
Recruitment maneuvers in acute respiratory distress syndrome: The safe way is the best way  
Raquel S Santos, Pedro L Silva, Paolo Pelosi, Patricia RM Rocco 
World J Crit Care Med 4(4):278-286. Published online Nov 4, 2015. doi: 10.5492/wjccm.v4.i4.278
14
15
Fluid and electrolyte overload in critically ill patients: An overview  
Bruno Adler Maccagnan Pinheiro Besen, André Luiz Nunes Gobatto, Lívia Maria Garcia Melro, Alexandre Toledo Maciel, Marcelo Park 
World J Crit Care Med 4(2):116-129. Published online May 4, 2015. doi: 10.5492/wjccm.v4.i2.116
16
Severe trauma in the geriatric population  
Juan Antonio Llompart-Pou, Jon Pérez-Bárcena, Mario Chico-Fernández, Marcelino Sánchez-Casado, Joan Maria Raurich 
World J Crit Care Med 6(2):99-106. Published online May 4, 2017. doi: 10.5492/wjccm.v6.i2.99
17
Steps to consider in the approach and management of critically ill patient with spontaneous intracerebral hemorrhage  
Daniel Agustin Godoy, Gustavo Rene Piñero, Patricia Koller, Luca Masotti, Mario Di Napoli 
World J Crit Care Med 4(3):213-229. Published online Aug 4, 2015. doi: 10.5492/wjccm.v4.i3.213
18
Tumor lysis syndrome: A clinical review  
Aibek E Mirrakhimov, Prakruthi Voore, Maliha Khan, Alaa M Ali 
World J Crit Care Med 4(2):130-138. Published online May 4, 2015. doi: 10.5492/wjccm.v4.i2.130
19
20
Extracorporeal membrane oxygenation for pediatric respiratory failure: History, development and current status  
Anna Maslach-Hubbard, Susan L Bratton 
World J Crit Care Med 2(4):29-39. Published online Nov 4, 2013. doi: 10.5492/wjccm.v2.i4.29
21
Severe sepsis and septic shock in the elderly: An overview  
Prashant Nasa, Deven Juneja, Omender Singh 
World J Crit Care Med 1(1):23-30. Published online Feb 4, 2012. doi: 10.5492/wjccm.v1.i1.23
22
Iatrogenic pneumothorax related to mechanical ventilation  
Chien-Wei Hsu, Shu-Fen Sun 
World J Crit Care Med 3(1):8-14. Published online Feb 4, 2014. doi: 10.5492/wjccm.v3.i1.8
23
Anticoagulant modulation of inflammation in severe sepsis  
Karen S Allen, Eva Sawheny, Gary T Kinasewitz 
World J Crit Care Med 4(2):105-115. Published online May 4, 2015. doi: 10.5492/wjccm.v4.i2.105
24
Implementation of enteral feeding protocol in an intensive care unit: Before-and-after study  
Martin Padar, Gerli Uusvel, Liis Starkopf, Joel Starkopf, Annika Reintam Blaser 
World J Crit Care Med 6(1):56-64. Published online Feb 4, 2017. doi: 10.5492/wjccm.v6.i1.56
25
Early debridement and delayed primary vascularized cover in forearm electrical burns: A prospective study  
Aniruddh Mene, Gautam Biswas, Atul Parashar, Anish Bhattacharya 
World J Crit Care Med 5(4):228-234. Published online Nov 4, 2016. doi: 10.5492/wjccm.v5.i4.228
26
Characteristics of postintensive care syndrome in survivors of pediatric critical illness: A systematic review  
Elizabeth A Herrup, Beth Wieczorek, Sapna R Kudchadkar 
World J Crit Care Med 6(2):124-134. Published online May 4, 2017. doi: 10.5492/wjccm.v6.i2.124
27
Neuroprotective measures in children with traumatic brain injury  
Shruti Agrawal, Ricardo Garcia Branco 
World J Crit Care Med 5(1):36-46. Published online Feb 4, 2016. doi: 10.5492/wjccm.v5.i1.36
28
Independent lung ventilation: Implementation strategies and review of literature  
Sheri Berg, Edward A Bittner, Lorenzo Berra, Robert M Kacmarek, Abraham Sonny 
World J Crit Care Med 8(4):49-58. Published online Jul 31, 2019. doi: 10.5492/wjccm.v8.i4.49
29
Severe scrub typhus infection: Clinical features, diagnostic challenges and management  
John Victor Peter, Thomas I Sudarsan, John Anthony J Prakash, George M Varghese 
World J Crit Care Med 4(3):244-250. Published online Aug 4, 2015. doi: 10.5492/wjccm.v4.i3.244
30
Adverse events in critical care: Search and active detection through the Trigger Tool  
Francisco J Molina, Paula T Rivera, Alejandro Cardona, Diana C Restrepo, Oralia Monroy, Daniel Rodas, Juan G Barrientos 
World J Crit Care Med 7(1):9-15. Published online Feb 4, 2018. doi: 10.5492/wjccm.v7.i1.9
31
Controversies in fluid therapy: Type, dose and toxicity  
Robert C McDermid, Karthik Raghunathan, Adam Romanovsky, Andrew D Shaw, Sean M Bagshaw 
World J Crit Care Med 3(1):24-33. Published online Feb 4, 2014. doi: 10.5492/wjccm.v3.i1.24
32
Critical care management and intensive care unit outcomes following cytoreductive surgery with hyperthermic intraperitoneal chemotherapy  
Sumit Kapoor, Adel Bassily-Marcus, Rafael Alba Yunen, Parissa Tabrizian, Sabrine Semoin, Joseph Blankush, Daniel Labow, John Oropello, Anthony Manasia, Roopa Kohli-Seth 
World J Crit Care Med 6(2):116-123. Published online May 4, 2017. doi: 10.5492/wjccm.v6.i2.116
33
34
Timing, method and discontinuation of hydrocortisone administration for septic shock patients  
Miguel A Ibarra-Estrada, Quetzalcóatl Chávez-Peña, Claudia I Reynoso-Estrella, Jorge Rios-Zermeño, Pável E Aguilera-González, Miguel A García-Soto, Guadalupe Aguirre-Avalos 
World J Crit Care Med 6(1):65-73. Published online Feb 4, 2017. doi: 10.5492/wjccm.v6.i1.65
35
Brain-lung crosstalk: Implications for neurocritical care patients  
Ségolène Mrozek, Jean-Michel Constantin, Thomas Geeraerts 
World J Crit Care Med 4(3):163-178. Published online Aug 4, 2015. doi: 10.5492/wjccm.v4.i3.163
36
Vasopressin in vasoplegic shock: A systematic review  
Andrew J Webb, Mohamed O Seisa, Tarek Nayfeh, Patrick M Wieruszewski, Scott D Nei, Nathan J Smischney 
World J Crit Care Med 9(5):88-98. Published online Dec 18, 2020. doi: 10.5492/wjccm.v9.i5.88
37
Acute cor pulmonale in patients with acute respiratory distress syndrome: A comprehensive review  
Kay Choong See 
World J Crit Care Med 10(2):35-42. Published online Mar 9, 2021. doi: 10.5492/wjccm.v10.i2.35
38
39
Experience with hemoadsorption (CytoSorb®) in the management of septic shock patients  
Yatin Mehta, Chitra Mehta, Ashish Kumar, Joby Varghese George, Aditi Gupta, Saurabh Nanda, Gourav Kochhar, Arun Raizada 
World J Crit Care Med 9(1):1-12. Published online Jan 31, 2020. doi: 10.5492/wjccm.v9.i1.1
40
Clinical characteristics and outcomes associated with nasal intermittent mandatory ventilation in acute pediatric respiratory failure  
Billy C Wang, Theodore Pei, Cheryl B Lin, Rong Guo, David Elashoff, James A Lin, Carol Pineda 
World J Crit Care Med 7(4):46-51. Published online Sep 7, 2018. doi: 10.5492/wjccm.v7.i4.46
41
Inhaling muscle spray: A rising trend of abuse  
Sohil Pothiawala, Chong King Yong, Rabind Charles 
World J Crit Care Med 10(3):43-46. Published online May 9, 2021. doi: 10.5492/wjccm.v10.i3.43
42
Modeling cardiac arrest and resuscitation in the domestic pig  
Brandon H Cherry, Anh Q Nguyen, Roger A Hollrah, Albert H Olivencia-Yurvati, Robert T Mallet 
World J Crit Care Med 4(1):1-12. Published online Feb 4, 2015. doi: 10.5492/wjccm.v4.i1.1
43
Prognostic categorization of intensive care septic patients  
Mohamed Ezzat Moemen 
World J Crit Care Med 1(3):67-79. Published online Jun 4, 2012. doi: 10.5492/wjccm.v1.i3.67
44
Invasive candidiasis in critical care setting, updated recommendations from “Invasive Fungal Infections-Clinical Forum”, Iran  
Ashraf Elhoufi, Arezoo Ahmadi, Amir Mohammad Hashem Asnaashari, Mohammad Ali Davarpanah, Behrooz Farzanegan Bidgoli, Omid Moradi Moghaddam, Mohammad Torabi-Nami, Saeed Abbasi, Malak El-Sobky, Ali Ghaziani, Mohammad Hossein Jarrahzadeh, Reza Shahrami, Farzad Shirazian, Farhad Soltani, Homeira Yazdinejad, Farid Zand 
World J Crit Care Med 3(4):102-112. Published online Nov 4, 2014. doi: 10.5492/wjccm.v3.i4.102
45
Clinical decision support for drug related events: Moving towards better prevention  
Sandra L Kane-Gill, Archita Achanta, John A Kellum, Steven M Handler 
World J Crit Care Med 5(4):204-211. Published online Nov 4, 2016. doi: 10.5492/wjccm.v5.i4.204
46
Determination of functional prognosis in hospitalized patients following an intensive care admission  
Natália A Ferreira, Agnaldo José Lopes, Arthur S Ferreira, George Ntoumenopoulos, Jerffesson Dias, Fernando S Guimaraes 
World J Crit Care Med 5(4):219-227. Published online Nov 4, 2016. doi: 10.5492/wjccm.v5.i4.219
47
Epidemiology of electrical burns and its impact on quality of life - the developing world scenario  
Giriraj Gandhi, Atul Parashar, Ramesh K Sharma 
World J Crit Care Med 11(1):58-69. Published online Jan 9, 2022. doi: 10.5492/wjccm.v11.i1.58
48
Effects of mineralocorticoid receptor antagonists on responses to hemorrhagic shock in rats  
Kanako Yamamoto, Takashi Yamamoto, Masayuki Takamura, Soichiro Usui, Hisayoshi Murai, Shuichi Kaneko, Takumi Taniguchi 
World J Crit Care Med 7(1):1-8. Published online Feb 4, 2018. doi: 10.5492/wjccm.v7.i1.1
49
Optimizing the value of measuring inferior vena cava diameter in shocked patients  
Fikri M Abu-Zidan 
World J Crit Care Med 5(1):7-11. Published online Feb 4, 2016. doi: 10.5492/wjccm.v5.i1.7
50
Management of gastrointestinal bleed in the intensive care setting, an updated literature review  
Vignesh K Nagesh, Sai Priyanka Pulipaka, Ruchi Bhuju, Emelyn Martinez, Shruthi Badam, Gomathy Aarthy Nageswaran, Hadrian Hoang-Vu Tran, Daniel Elias, Charlene Mansour, Jaber Musalli, Sanket Bhattarai, Lokeash Subramani Shobana, Tannishtha Sethi, Ritvik Sethi, Namrata Nikum, Chinmay Trivedi, Amer Jarri, Colin Westman, Nazir Ahmed, Shawn Philip, Simcha Weissman, Jonathan Weinberger, Ayrton I Bangolo 
World J Crit Care Med 14(1):101639. Published online Mar 9, 2025. doi: 10.5492/wjccm.v14.i1.101639