Born in Turin, Italy on June 11, 1948 Full Professor of Gastroenterology, University of Pisa, Associate Senior Researcher, Institute of Biostructure and Bioimaging (IBB), National Research Council (CNR), Italy Professional and Scientific Career: Research Fellow, Assistant and Associate Professor of Gastroenterology at the Gastroenterology Department of the University Hospitals of Turin, Italy from 1975 to 1997 (Head: Prof. Giorgio Verme): during this period director of the Laboratory of Liver Pathology. Visiting Scientist at the Hepatitis Section of the National Institute of Allergy and Infectious Diseases, NIH, Bethesda Maryland, USA (Head: Prof. R.H. Purcell) and at the Division of Molecular Virology and Immunology of Georgetown University Rockville, MD, USA (Head: Prof. J.L. Gerin) from 1979-1981. From 1997 to 2001 Director of the Gastroenterology and Hepatology Unit at the University Hospital of Pisa, Italy and coordinator of the Functional Area of Medicine. From 2001-2010 Chief Scientific Officer of the Foundation “Ca Granda” National Institute of Translational Research (IRCCS) Ospedale Maggiore Policlinico of Milan, Italy. From 2010 to 2016 Director of General Medicine 2, Liver and Digestive Disease, University Hospital of Pisa, Italy. Other Duties:1987-1990 Member of the Scientific Committee of the Italian Association for the Study of the Liver (AISF) and Secretary of AISF from 1988 to 1990.1988-1990 Representative of the European Association for the Study of the Liver (EASL) in the International Association for the Study of the Liver (IASL).1999-2002 Member of the Ethic Committee of the University Hospital of Pisa. 1999-2005 Member of the Evaluation Committee of the University Hospital of Pisa.1999-2000 Member of the Ministry of Health Commission for Xenotransplants.2001-2010 Member of the Ethic Committee of the Foundation “Ca Granda” National Institute of Translational Research (IRCCS) Ospedale Maggiore Policlinico of Milan.2001-2003 Italian Member of the Committee of Experts on Reviewing the Revised European Social Charter (Article 11), Council of Europe, Bruxelles. 2002-2003 Component of the Committee for VI Strategic Program for Education, Research and Technology for Health of the Ministry of University and Research of Italy. 2002-2006 President of the National Consortium for Stem Cells “Constem”. 2003-2006 Expert of the Superior Council of Health of Italy. 2003-2006 Component of the Scientific Committee of the Istituto Superiore di Sanità (ISS), National Institute of Health of Italy. 2002-2008 Component of the Ministry Commission for Phase 1 Studies. 2010-2013 Member of the Evaluation Committee of the University of Pisa. 2010-2016 Director of the Centre for the Clinical Use of Stem Cells of the University Hospital of Pisa. 2002-to date Component of the Scientific Committee of the Foundation National Centre for Adrotherapy (CNAO). 2014-2019 Chief Scientific Officer of the UPMC Institute for Health, Chianciano Terme, Italy. 2016-to date Senior Researcher Associate at the Biostructure and Bioimaging Institute (IBB) of the National Research Council (CNR) of Italy Major Scientific Achievements