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©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Nov 16, 2022; 10(32): 11993-11999
Published online Nov 16, 2022. doi: 10.12998/wjcc.v10.i32.11993
Published online Nov 16, 2022. doi: 10.12998/wjcc.v10.i32.11993
Minimal change disease caused by polycythemia vera: A case report
Li Xu, Li-Li Lu, Jian-Dong Gao, Department of Nephrology, Shuguang Hospital Affiliated to the Shanghai University of Traditional Chinese Medicine, TCM Institute of Kidney Disease, Shanghai University of Traditional Chinese Medicine, Key Laboratory of Liver and Kidney Diseases (Shanghai University of Traditional Chinese Medicine), Ministry of Education, Shanghai Key Laboratory of Traditional Chinese Clinical Medicine (20DZ2272200), Shanghai 201203, China
Author contributions: Xu L was responsible for writing the manuscript and data analysis; Lu LL helped with document retrieval; Gao JD was responsible for supervision; all authors agree with the final version of the manuscript.
Supported by the National Natural Science Foundation of China , No. 81874437 and 81904126 ; Science and Technology Commission of Shanghai Municipality , No. 20Y21901800 .
Informed consent statement: Informed written consent was obtained from the patient for the publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jian-Dong Gao, PhD, Professor, Department of Nephrology, Shuguang Hospital Affiliated to the Shanghai University of Traditional Chinese Medicine, TCM Institute of Kidney Disease, Shanghai University of Traditional Chinese Medicine, Key Laboratory of Liver and Kidney Diseases (Shanghai University of Traditional Chinese Medicine), Ministry of Education, Shanghai Key Laboratory of Traditional Chinese Clinical Medicine (20DZ2272200), No. 528 Road ZhangHeng, Shanghai 201203, China. jiandong.gao@shutcm.edu.cn
Received: August 24, 2022
Peer-review started: August 24, 2022
First decision: September 23, 2022
Revised: September 27, 2022
Accepted: October 19, 2022
Article in press: October 19, 2022
Published online: November 16, 2022
Peer-review started: August 24, 2022
First decision: September 23, 2022
Revised: September 27, 2022
Accepted: October 19, 2022
Article in press: October 19, 2022
Published online: November 16, 2022
Core Tip
Core Tip: Polycythemia vera (PV) is a myeloproliferative neoplasm that can influence the immune system and affect organs such as the kidneys. This is the first report of PV-associated minimal change disease. In our case, hydroxyurea administration was effective and proteinuria remission was achieved. Therefore, we infer there may be a causal relationship between PV and minimal change disease.