Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jan 21, 2022; 10(3): 1093-1098
Published online Jan 21, 2022. doi: 10.12998/wjcc.v10.i3.1093
Epibulbar osseous choristoma: Two case reports
Yu-Chen Wang, Zi-Zhen Wang, De-Bo You, Wei Wang
Yu-Chen Wang, De-Bo You, Wei Wang, Department of Ophthalmology, Peking University Third Hospital, Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Beijing 100191, China
Zi-Zhen Wang, Peking University Health Science Center, Beijing 100191, China
Author contributions: Wang YC reviewed the literature, collected the data, and drafted the manuscript; Wang ZZ and Wang W revised the reviewed manuscript; and You DB gave final approval of the version to be submitted and any revised version.
Informed consent statement: The participants have consented to the submission of the study to the journal.
Conflict-of-interest statement: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as potential conflict of interests.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: De-Bo You, MD, PhD, Doctor, Professor, Department of Ophthalmology, Peking University Third Hospital, Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, No. 49 North Garden Road, Haidian District, Beijing 100191, China.
Received: July 13, 2021
Peer-review started: July 13, 2021
First decision: October 22, 2021
Revised: October 24, 2021
Accepted: December 23, 2021
Article in press: December 23, 2021
Published online: January 21, 2022

Choristoma is a rare, benign, congenital proliferative tumor, with osseous choristoma being the rarest. Although the tumor is benign, effective identification is needed for its diagnosis and treatment. Here, we report the diagnosis and successful surgical treatment of two patients with osseous choristoma.


Two patients, a young female and young male patient, were found to have a mass on the ocular surface. The tumor presented on the superior temporal bulbar conjunctiva in the first patient and on the upper eyelid in the second patient. Ultrasound biomicroscopy detected a strong echo with clear boundaries covering the lower echo, and computed tomography examination revealed calcification. Both patients underwent surgery, and histopathological evaluation of the mass showed osseous choristoma. They were treated by excision and subsequently cured.


Osseous choristomas are usually asymptomatic. Our patients were cured immediately after surgery, suggesting that surgical treatment is an effective strategy.

Keywords: Osseous choristoma, Epibulbar choristoma, Prevelence, Treatment of choristoma, Case report

Core Tip: In this paper, we report two cases of osseous choristoma. Osseous choristoma is mostly seen in young adults and asymptomatic. Physical examination showed a hard mass, and pathology reported the bone structure in the tumor. The prognosis of the disease was good, and no recurrence was observed during follow-up.