Relationship between expression of laminin and pathological features in human colorectal carcinoma

Table 1 Tumor grading and laminin staining patterns

Tumor grade	n	Laminin staining pattern
		+ + to + + +	- to +
Well differenciated	20	16 (80.0%)	4 (20.0%)a
Moderately differenticated	21	12 (47.1%)	9 (42.9%)a
Poorly differenticted	22	3 (13.6%)	19 (86.4%)

^aP < 0.01 vs poorly differentiated tumor.

Table 2 Tumor stage and laminin staining pattern

Tumor grade	n	Laminin staining pattern
		+ + to + + +	- to +
Dukes’s stage A	36	20 (45.6%)	16 (44.4%)
Dukes’s stage B	6	3 (50.0%)	3 (50.0%)a
Dukes’s stage C	21	8 (38.1%)	13 (61.9%)a

^aP > 0.05 vs Dukes’s stage A tumor.

Table 3 Tumor invasion depth and laminin staining pattern

Depth of invasion	n	Laminin staining pattern
		+ + to + + +	- to +
Mucosa and submucosa	4	3 (75.0%)	1 (25.0%)
Muscularis	32	17 (53.1%)	15 (46.9%)a
Serosa and subserosa	27	11 (40.7%)	16 (59.3%)a

^aP > 0.05 vs tumor not extended beyond the submucosa.