Case Report
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Mar 26, 2020; 8(6): 1164-1171
Published online Mar 26, 2020. doi: 10.12998/wjcc.v8.i6.1164
Hepatoid adenocarcinoma of the stomach: Thirteen case reports and review of literature
Zheng-Rong Zhang, Jian Wu, Han-Wen Li, Tao Wang
Zheng-Rong Zhang, Jian Wu, Han-Wen Li, Tao Wang, Department of Gastrointestinal Surgery, The First Affiliated Hospital of Wannan Medical College, Wuhu 241000, Anhui Province, China
Author contributions: Zhang ZR was a major contributor in acquiring the data, performing the literature search, and drafting the manuscript; Li HW and Wang T contributed to analysis of the data and preparation and revision of the manuscript; Wu J provided critical revision of the manuscript; all authors read and approved the final manuscript.
Informed consent statement: Informed consent statement was obtained from the patients.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
CARE Checklist (2016) statement: The manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Jian Wu, BMed, Surgeon, Department of Gastrointestinal Surgery, The First Affiliated Hospital of Wannan Medical College, 2 Zheshan West Road, Wuhu 241000, Anhui Province, China. wj4966@126.com
Received: December 23, 2019
Peer-review started: December 23, 2019
First decision: February 20, 2020
Revised: March 9, 2020
Accepted: March 14, 2020
Article in press: March 14, 2020
Published online: March 26, 2020
Core Tip

Core tip: Hepatoid adenocarcinoma of the stomach (HAS) is a rare special type of gastric cancer that is prone to lymph node and liver metastases and has a poor prognosis. In the majority of HAS cases, the ability to produce the alpha-fetoprotein and the serum levels of alpha-fetoprotein may be elevated during the early stages. In this study, we evaluated the clinical data, pathological features, treatment results, and prognosis of HAS patients.