Case Report
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jan 26, 2020; 8(2): 410-414
Published online Jan 26, 2020. doi: 10.12998/wjcc.v8.i2.410
Eye metastasis in lung adenocarcinoma mimicking anterior scleritis: A case report
Hua-Fei Chen, Wen-Xian Wang, Xiao-Feng Li, Li-Xin Wu, You-Cai Zhu, Kai-Qi Du, Chun-Wei Xu
Hua-Fei Chen, Xiao-Feng Li, Li-Xin Wu, You-Cai Zhu, Kai-Qi Du, Thoracic Disease Center, Zhejiang Rongjun Hospital, Jiaxing 314000, Zhejiang Province, China
Wen-Xian Wang, Department of Chemotherapy, Zhejiang Cancer Hospital, Hangzhou 310022, Zhejiang Province, China
Chun-Wei Xu, Department of Pathology, Fujian Cancer Hospital, Fujian Medical University Cancer Hospital, Fuzhou 350014, Fujian Province, China
Author contributions: All authors equally contributed to this paper.
Supported by Science and Technology Planning Project of Zhejiang Province, No. LGF19H160002; Medical Scientific Research Foundation of Zhejiang Province of China, No. 2019RC027; Scientific Research Foundation of Zhejiang Medical Association, No. 2018ZYC-B5; Technology Bureau of Jiaxing City of Zhejiang Province, No. 2017BY18050, No. 2018AD32163, and No. 2019AD32266; and Xisike-Hanson Cancer Research Foundation, No. Y-HS2019-20.
Informed consent statement: Written informed consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Chun-Wei Xu, MD, PhD, Professor, Department of Pathology, Fujian Cancer Hospital, Fujian Medical University Cancer Hospital, No. 420, Fuma Road, Fuzhou 350014, Fujian Province, China.
Received: October 17, 2019
Peer-review started: October 17, 2019
First decision: December 4, 2019
Revised: December 4, 2019
Accepted: December 22, 2019
Article in press: December 22, 2019
Published online: January 26, 2020
Core Tip

Core tip: The eye is a rare site for lung cancer metastasis. We report the case of a patient with lung adenocarcinoma and ocular metastasis. Brain magnetic resonance imaging showed an abnormal signal in the right eye. Based on next generation sequencing of the surgical specimen, the patient was shown to have a KRAS point mutation (p.G12D). The clinical feature and treatment of the disease are presented and discussed.