Published online Jan 26, 2020. doi: 10.12998/wjcc.v8.i2.410
Peer-review started: October 17, 2019
First decision: December 4, 2019
Revised: December 4, 2019
Accepted: December 22, 2019
Article in press: December 22, 2019
Published online: January 26, 2020
The eye is a rare site for lung cancer metastasis. Indeed, ocular metastasis is one of the greatest challenges to quality of life in a cancer patient. Here we present a patient with lung adenocarcinoma and ocular metastasis.
The patient was a 70-year-old man diagnosed with lung adenocarcinoma who developed eye metastasis mimicking anterior scleritis. Brain magnetic resonance imaging showed an abnormal signal in the right eye. Based on next generation sequencing of the surgical specimen, the patient was shown to have a KRAS point mutation (p.G12D).
Multidiscipline expertise collaboration is needed to make the early diagnosis and determine the prompt treatment in patients. We hope to increase the awareness of the possibility of lung cancer metastasizing to the eye.
Core tip: The eye is a rare site for lung cancer metastasis. We report the case of a patient with lung adenocarcinoma and ocular metastasis. Brain magnetic resonance imaging showed an abnormal signal in the right eye. Based on next generation sequencing of the surgical specimen, the patient was shown to have a KRAS point mutation (p.G12D). The clinical feature and treatment of the disease are presented and discussed.