Case Report
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Oct 6, 2020; 8(19): 4667-4675
Published online Oct 6, 2020. doi: 10.12998/wjcc.v8.i19.4667
Localized primary gastric amyloidosis: Three case reports
Xue-Mei Liu, Lian-Jun Di, Jia-Xing Zhu, Xing-Long Wu, Hong-Ping Li, Hui-Chao Wu, Bi-Guang Tuo
Xue-Mei Liu, Lian-Jun Di, Jia-Xing Zhu, Hong-Ping Li, Hui-Chao Wu, Bi-Guang Tuo, Department of Gastroenterology, Affiliated Hospital of Zunyi Medical University, Zunyi 563003, Guizhou Province, China
Xing-Long Wu, Department of Pathology, Affiliated Hospital of Zunyi Medical University, Zunyi 563003, Guizhou Province, China
Author contributions: Liu XM wrote the manuscript; Liu XM and Di LJ diagnosed the patient and performed the treatment; Tuo BG revised the article; Zhu JX and Wu XL contributed to the histopathology and immunohistochemistry; and all other authors reviewed and approved the final manuscript to be published.
Supported by the National Natural Science Foundation of China, No. 81860103, No. 81560456, No. 81660098 and No. 81572438; and the Outstanding Scientific Youth Fund of Guizhou Province, No. 2017-5608.
Informed consent statement: Informed written consent was obtained from the patients for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare no conflicts of interest.
CARE Checklist (2016) statement: The manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Bi-Guang Tuo, Department of Gastroenterology, Affiliated Hospital, Zunyi Medical University, No. 149 Dalian Road, Zunyi 563003, Guizhou Province, China. tuobiguang@aliyun.com
Received: May 23, 2020
Peer-review started: May 23, 2020
First decision: June 18, 2020
Revised: July 27, 2020
Accepted: August 20, 2020
Article in press: August 20, 2020
Published online: October 6, 2020
Core Tip

Core Tip: Localized gastric amyloidosis is a very rare metabolic disease. We report a series of three cases of localized gastric amyloidosis mimicking gastric mucosa-associated lymphoid tissue lymphoma on endoscopic examination that were evaluated over the past ten years in our hospital. Esophagogastroduodenoscopy, endoscopic ultrasound, computed tomography and endoscopic submucosal dissection were performed in different patients, the histopathological examination resulted in the diagnosis of localized gastric amyloidosis. However, the different detection times of this rare disease in three patients resulted in three totally different outcomes, indicating that early detection, diagnosis and treatment of localized gastric amyloidosis result in an excellent prognosis.