Case Report
Copyright ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Aug 6, 2019; 7(15): 2081-2086
Published online Aug 6, 2019. doi: 10.12998/wjcc.v7.i15.2081
Oncogenic osteomalacia caused by a phosphaturic mesenchymal tumor of the femur: A case report
Dong Tang, Xiao-Man Wang, Yong-Sheng Zhang, Xiao-Xiao Mi
Dong Tang, Department of Medical Imaging (Radiology), The Affiliated Hospital of Hangzhou Normal University, Hangzhou 310015, Zhejiang Province, China
Xiao-Man Wang, Department of Ultrasound, The Affiliated Hospital of Hangzhou Normal University, Hangzhou 310015, Zhejiang Province, China
Yong-Sheng Zhang, Department of Radiology, Hangzhou Hospital of Traditional Medicine, Hangzhou 310015, Zhejiang Province, China
Yong-Sheng Zhang, Department of Radiology, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310015, Zhejiang Province, China
Xiao-Xiao Mi, Institute of Translational Medicine, The Affiliated Hospital of Hangzhou Normal University, Hangzhou 310015, Zhejiang Province, China
Author contributions: All authors contributed significantly to this case report; Mi XX and Tang D conceived and designed the case report with great input from Wang XM and Zhang YS; Tang D and Wang XM provided the radiological imaging and pathological analyses; Zhang YS was involved in the biomedical analysis; Mi XX wrote the manuscript with input from Wang XM, Zhang YS, and Tang D.
Informed consent statement: Informed written consent was obtained from the patient for publication of this case report and accompanying images.
Conflict-of-interest statement: The authors declare that they have no competing interests.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Xiao-Xiao Mi, PhD, Chief Technician, Institute of Translational Medicine, The Affiliated Hospital of Hangzhou Normal University, 126 Wenzhou Road, Hangzhou 310015, Zhejiang Province, China. mixiaoxiao1987@163.com
Telephone: +86-571-88303635
Supported by Research Fund of Hangzhou Normal University Affiliated Hospital.
Received: February 2, 2019
Peer-review started: February 11, 2019
First decision: May 31, 2019
Revised: June 4, 2019
Accepted: June 20, 2019
Article in press: June 21, 2019
Published online: August 6, 2019
Core Tip

Core tip: Oncogenic osteomalacia caused by phosphaturic mesenchymal tumors is not easily identifiable or detectable due to its rarity and nonspecific presentations. Herein, we provide a successful example of diagnosis of phopshaturic mesenchymal tumor-induced oncogenic osteomalacia in a female patient who presented progressive bone pain. Our case emphasizes that histologically benign phosphaturic mesenchymal tumors that are responsible for oncogenic osteomalacia can also cause bone destruction.