Case Report
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Aug 16, 2025; 13(23): 102937
Published online Aug 16, 2025. doi: 10.12998/wjcc.v13.i23.102937
Liver function improvement after human placental extract injections in patients with chronic liver disease: Thirty case reports
Seung-Won Lee
Seung-Won Lee, Danaun Medical Clinic, Gwangmyeong-si 14262, Gyeonggi-do, South Korea
Author contributions: Lee SW designed and conducted the study and wrote the manuscript, read and approved the final version of the manuscript to be published.
Informed consent statement: This study was conducted without obtaining individual patient consent as it utilizes post-treatment data. As per institutional and privacy guidelines, we are unable to share any patient-identifiable information. Additionally, as per medical regulations, the first page of the patient records cannot be provided.
Conflict-of-interest statement: The author declares that they have no conflict of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Seung-Won Lee, MD, Danaun Medical Clinic, 896 Gwangmyeong-ro, Gwangmyeong-si 14262, Gyeonggi-do, South Korea. gclaennec@gmail.com
Received: November 4, 2024
Revised: March 22, 2025
Accepted: April 27, 2025
Published online: August 16, 2025
Processing time: 214 Days and 3.7 Hours
Core Tip

Core Tip: In this paper, we describe an innovative treatment method that involved the intravenous administration of 10 mL of human placental extract once or twice a week. This is the first case report on the use of placental extract in patients with chronic liver disease (CLD) through an innovative treatment method. This treatment method can be used to improve liver function in patients with CLD.