Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Nov 16, 2022; 10(32): 12045-12051
Published online Nov 16, 2022. doi: 10.12998/wjcc.v10.i32.12045
Langerhans cell histiocytosis involving only the thymus in an adult: A case report
Yi-Fan Li, Shao-Hui Han, Peng Qie, Qi-Fan Yin, Hui-En Wang
Yi-Fan Li, Shao-Hui Han, Peng Qie, Qi-Fan Yin, Hui-En Wang, Department of Thoracic Surgery, Hebei General Hospital, Shijiazhuang 050000, Hebei Province, China
Yi-Fan Li, Graduate School, Hebei North University, Zhangjiakou 075000, Hebei Province, China
Author contributions: Li YF and Han SH contributed to manuscript writing and editing; Qie P and Yin QF contributed to manuscript data collection; Wang HE contributed to conceptualization and supervision; all authors have read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patient and her family for publication of this report and any accompanying images.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hui-En Wang, MM, Associate Chief Physician, Associate Professor, Department of Thoracic Surgery, Hebei General Hospital, No. 348 West Heping Boulevard, Shijiazhuang 050000, Hebei Province, China. wanghe829@126.com
Received: August 20, 2022
Peer-review started: August 20, 2022
First decision: September 5, 2022
Revised: September 7, 2022
Accepted: October 12, 2022
Article in press: October 12, 2022
Published online: November 16, 2022
Core Tip

Core Tip: Langerhans cell histiocytosis (LCH) is an infrequent clinical hematological disorder. The gold standard for diagnosis is surgical biopsy for pathological examination and immunohistochemical analysis. We report a rare case of LCH with monosystemic involvement, which, when combined with previous case reports of LCH, reveals that LCH involving only the thymus is extremely rare in adults. The imaging features are similar to those of thymoma and may provide additional diagnostic ideas in the detection of anterior mediastinal occupations.