Retrospective Study
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Oct 6, 2020; 8(19): 4349-4359
Published online Oct 6, 2020. doi: 10.12998/wjcc.v8.i19.4349
Managing acute appendicitis during the COVID-19 pandemic in Jiaxing, China
Yuan Zhou, Lu-Sha Cen
Yuan Zhou, Department of Gastrointestinal Surgery, The First Hospital of Jiaxing, Affiliated Hospital of Jiaxing University, Jiaxing 31400, Zhejiang Province, China
Lu-Sha Cen, Department of Ophthalmology, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310006, Zhejiang Province, China
Author contributions: Zhou Y and Cen LS contributed equally to this manuscript; Zhou Y participated in study design, drafted the manuscript, was involved in data collection, and assisted with data analysis; Cen LS participated in design, was involved in data collection, and supervised the study; All authors have read and approved the final version of the manuscript.
Supported by Jiaxing Key Discipline of Medicine-Oncology (Supporting Subject), No. 2019-zc-11.
Institutional review board statement: The study was reviewed and approved by the Ethics Committee of the First Hospital of Jiaxing.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: No conflict-of-interest statement declared.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at Cenlusa2@sina.com.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Lu-Sha Cen, MD, Attending Doctor, Department of Ophthalmology, The First Affiliated Hospital of Zhejiang Chinese Medical University, No. 54 Youdian Road, Hangzhou 310006, Zhejiang Province, China. cenlusa2@sina.com
Received: June 18, 2020
Peer-review started: June 18, 2020
First decision: July 24, 2020
Revised: August 5, 2020
Accepted: September 2, 2020
Article in press: September 2, 2020
Published online: October 6, 2020
ARTICLE HIGHLIGHTS
Research background

At present, coronavirus disease 19 (COVID-19) has profoundly influenced our routine surgical activities. How to handle acute appendicitis emergencies during this and future pandemics is emerging as an urgent issue.

Research motivation

There have been rare reports about acute appendicitis emergencies during COVID-19 pandemics. Our experience will help other surgeons or physicians choose ideal treatments for other emergencies or delays.

Research objectives

To assess the efficacy of the management of acute appendicitis during the COVID-19 pandemic.

Research methods

We retrospectively analyzed the clinical data of acute appendicitis patients admitted to The First Hospital of Jiaxing during the initial outbreak of COVID-19. Clinical data were also collected for the corresponding time frame from 2019. Preoperative management, intraoperative protective measures, and postoperative management data were conducted.

Research results

After screening, six patients were identified as unqualified due to fever, and their results of nucleic acid test were negative. Seventy-six patients were enrolled in the simple group, and 14 patients were enrolled in the complex group. The proportion of men with perforated appendicitis was higher in 2020 than that in 2019. The chief complaint duration for perforated appendicitis patients in 2020 was longer than that in 2019. The routine blood test showed white blood cell counts and neutrophil ratios were higher in perforated appendicitis patients in 2020 than in 2019. The ratio of open appendectomies to the amount of mean blood loss during surgery was greater in 2020 than in 2019. Online consultation after discharge was selected in 59 cases. No perioperative infection with COVID-19 or long-term postoperative complications were found.

Research conclusions

The management of acute appendicitis from Jiaxing effectively reduced the influence of the pandemic and minimized the risk of nosocomial infection.

Research perspectives

The delay in care and challenges we all are facing are not only in emergency surgeries but also in other health care specialties. We should make our clinical management compatible with the challenges and threats of this pandemic while trying to achieve the optimal therapeutic effect.