Published online Sep 6, 2019. doi: 10.12998/wjcc.v7.i17.2427
Peer-review started: March 28, 2019
First decision: August 1, 2019
Revised: August 15, 2019
Accepted: August 25, 2019
Article in press: August 26, 2019
Published online: September 6, 2019
Reduced level of physical activity, high-fat diet and skeletal muscle atrophy are key factors that are likely to contribute to deleterious changes in body composition and metabolic following spinal cord injury (SCI). Reduced caloric intake with lowering percentage macronutrients of fat and increasing protein intake may likely to improve body composition parameters and decrease ectopic adiposity after SCI.
Currently, there is no standard of care of established evidence on how to improve body composition parameters and to reduce ectopic adiposity after SCI.
To highlight the necessary dietary adjustments as far as caloric and macronutrient intakes responsible for improving body composition and metabolic profile following participation in a 16 wk clinical trial of administering low-dose testosterone replacement therapy in a male with SCI.
We, retrospectively, tracked the dietary habits and body composition parameters in a 31-year-old male with motor-complete T5 SCI after administering low-dose testosterone replacement therapy (TRT) for 16 wk. Detailed body composition was evaluated via dual energy x-ray absorptiometry and magnetic resonance imaging. Participant was asked to turn in weekly 5 d dietary recalls to measure total energy intake, percentage carbohydrate, percentage fat, percentage protein, and total soluble fiber intake.
Lowering caloric intake by 25% and fat intake by 6.5% resulted in decreased body weight, total and regional body fat mass and ectopic adiposity. Both lean mass and BMR remained physiologically unchanged following the 16 wk intervention.
The current case report highlighted the significance of reducing caloric intake and manipulating macronutrients with TRT on the changes in total and regional body composition in a male with SCI.
The current case report may serve as supporting evidence for future clinical trial that may target manipulation of dietary intake with and without ergogenic aids similar to exercise and TRT to improve cardio-metabolic profile in persons with SCI.