Published online Aug 6, 2019. doi: 10.12998/wjcc.v7.i15.2058
Peer-review started: April 16, 2019
First decision: May 9,2019
Revised: June 17, 2019
Accepted: June 27, 2019
Article in press: June 27,2019
Published online: August 6, 2019
Solitary rectal ulcer syndrome (SRUS) is a rare rectal disorder characterized by bloody mucus in the stool, difficulty in defecation, pain, and anal swelling. To date, the etiology of this syndrome remains not well understood and the diagnosis is frequently confused with other disorders, making treatment a clinical challenge.
A 50-year-old woman presented to our hospital with a 40-d history of bloody mucus in the stool and anal swelling. SRUS was suspected. Rectoscopy revealed a large, severe ulcerous lesion. Histologically, the lesion was characterized as chronic ulcer without clear tumor cells, and the final diagnosis of SRUS was made. The patient was treated with Chinese medicine therapy, with administration of Tong Xie Yao Fang. After 3 wk of treatment, the symptoms improved significantly. At 2-mo follow-up, rectoscopy in a local hospital showed healed ulcer scars without obvious protrusion 3 cm from the anal verge.
Chinese medicine therapy represents a potential treatment of SRUS with predominant rectal bleeding, mucinous discharge, and anal swelling pain.
Core tip: Solitary rectal ulcer syndrome (SRUS) is a benign but uncommon rectal disorder. We present the case of a 50-year-old woman who suffered from SRUS for 40 d, with the symptoms of bloody mucous in the stools and anal swelling. Following our success of treatment with modified Tong Xie Yao Fang, we discuss how this traditional Chinese medicine prescription might be an effective treatment strategy for SRUS with this symptom profile.