Copyright ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jul 26, 2019; 7(14): 1775-1783
Published online Jul 26, 2019. doi: 10.12998/wjcc.v7.i14.1775
Endoscopic ultrasound-guided fine-needle aspiration biopsy - Recent topics and technical tips
Kazuya Matsumoto, Yohei Takeda, Takumi Onoyama, Soichiro Kawata, Hiroki Kurumi, Hiroki Koda, Taro Yamashita, Hajime Isomoto
Kazuya Matsumoto, Division of Internal Medicine, Irisawa Medical Clinic, Matsue 690-0025, Japan
Kazuya Matsumoto, Yohei Takeda, Takumi Onoyama, Soichiro Kawata, Hiroki Kurumi, Hiroki Koda, Taro Yamashita, Hajime Isomoto, Department of Multidisciplinary Internal Medicine, Tottori University, Yonago 683-8504, Japan
Author contributions: Matsumoto K drafted the manuscript; Matsumoto K and Takeda Y conceived and designed the study; Onoyama T, Kawata S and Kurumi H collected the data; Koda M and Yamashita T analyzed and interpreted the data; Isomoto H revised the manuscript.
Conflict-of-interest statement: No potential conflicts of interest relevant to this article were reported.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Kazuya Matsumoto, MD, PhD, Director, Division of Internal Medicine, Irisawa Medical Clinic, 285-6 Yawata-cho, Matsue 690-0025, Japan.
Telephone: +81-852-388211 Fax: +81-852-388210
Received: March 20, 2019
Peer-review started: March 20, 2019
First decision: May 7, 2019
Revised: June 17, 2019
Accepted: July 2, 2019
Article in press: July 3, 2019
Published online: July 26, 2019

Endoscopic ultrasound-guided fine-needle aspiration biopsy (EUS-FNA) is a useful procedure that enables reliable pathological diagnoses of pancreatobiliary diseases, subepithelial lesions, and swollen lymph nodes. In recent years, a pathological diagnosis based on EUS-FNA has made it possible to provide accurate treatment methods not only in these fields, but also in respiratory organs and otorhinolaryngology. This review discusses the latest topics pertaining to EUS-FNA as well as procedural tips.

Keywords: Endoscopic ultrasound-guided fine-needle aspiration biopsy, Cytology, Pathology, Pancreatobiliary diseases, Subepithelial lesions, Lymph nodes

Core tip: In the era of cyto-pathological diagnosis of various malignant diseases, endoscopic ultrasound-guided fine-needle aspiration biopsy (EUS-FNA) represents the most promising procedure for diagnosing various malignant diseases. However, to date, no reports have compared the utility, faults, and techniques of this procedure. In this review we highlight the recent topics and technical tips of EUS-FNA in the diagnostic process of various diseases, especially those which require tissue-based diagnosis to determine treatment.