Published online Jul 6, 2022. doi: 10.12998/wjcc.v10.i19.6750
Peer-review started: February 28, 2022
First decision: April 8, 2022
Revised: April 19, 2022
Accepted: April 28, 2022
Article in press: April 28, 2022
Published online: July 6, 2022
Tumor-to-tumor metastasis (TTM) is an uncommon condition. Only a few cases of renal cell carcinoma (RCC) as donor tumor of TTM have been reported in literature, and none of these studies have described RCC metastasizing to synchronous pheochromocytoma (PCC).
The patient was a 54-year-old woman who presented with recurrent dull abdominal pain for six months, which was further aggravated for one more month. Enhanced computed tomography revealed a tumor mass in the right kidney and another mass in the left retroperitoneum/adrenal gland. Histopa
This is the first case showing metastasis of CCRCC to PCC, thus leading to tumor-to-tumor metastasis.
Core Tip: Tumor-to-tumor metastasis (TTM) is uncommon. Only a limited number of cases in which renal cell carcinoma (RCC) is the donor tumor of TTM have been reported in the literature, and none of these studies have described RCC metastasizing to synchronous pheochromocytoma (PCC). Here, we report a unique case of clear cell renal cell carcinoma (CCRCC) metastasizing to contralateral retroperi