Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jun 26, 2022; 10(18): 6307-6313
Published online Jun 26, 2022. doi: 10.12998/wjcc.v10.i18.6307
Thyroid follicular renal cell carcinoma excluding thyroid metastases: A case report
Si-Cheng Wu, Xi-Ya Li, Bang-Jie Liao, Kun Xie, Wei-Min Chen
Si-Cheng Wu, Xi-Ya Li, Bang-Jie Liao, Kun Xie, Wei-Min Chen, Department of Urology, The First Affiliated Hospital of Nanchang University, Nanchang 330036, Jiangxi Province, China
Author contributions: Wu S and Xie K contributed equally to this work; Wu S, Li X, Liao B, Xie K and Chen W designed the research study; Wu S, Li X, Xie K and Liao B performed the research; Wu S and Xie K contributed new reagents and analytic tools; Li X, Xie K and Liao B analyzed the data and wrote the manuscript; all authors have read and approved the final manuscript.
Supported by Natural Science Foundation of Jiangxi Province, No. 2010GZY0806.
Informed consent statement: Consent was obtained from the patient and his family for publication of this report.
Conflict-of-interest statement: The authors declare that there are no conflicts of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Wei-Min Chen, Doctor, Chief Doctor, Surgeon, Surgical Oncologist, Department of Urology, The First Affiliated Hospital of Nanchang University, No. 17 Yongwai Zhengjie, Nanchang 330036, Jiangxi Province, China.
Received: December 31, 2021
Peer-review started: December 31, 2021
First decision: February 21, 2022
Revised: March 16, 2022
Accepted: April 21, 2022
Article in press: April 21, 2022
Published online: June 26, 2022

Thyroid follicular renal cell carcinoma is a special type of renal cell carcinoma newly recognized in recent years. It has attracted attention because of its unique histology, immunophenotype, and clinical characteristics. It has a very low incidence, and the number of case reports available for review is limited. Moreover, a thyroid mass with type of tumour is rare.


We report a case of a renal mass with a bilateral thyroid mass that was accidentally discovered in a 60-year-old man during physical examination. B-mode ultrasound showed a hypoechoic mass in the middle and lower parenchyma of the right kidney, and computed tomography showed an iso-density shadow tumour in the right kidney. Contrast agents had a significant continuous enhancement effect on the tumour, and the enhancement was not uniform. After partial nephrectomy, pathological analysis was performed to rule out the possibility that the renal tumour was caused by thyroid tumour metastasis. Needle biopsy of the thyroid tumour confirmed that the renal cell carcinoma was not related to the thyroid tumour. The patient was alive at the last postoperative follow-up.


This is the third published case in which thyroid tumour biopsy was performed to confirm that thyroid follicular renal cell carcinoma is not thyroid related.

Keywords: Renal cell carcinoma, Thyroid follicular renal cell carcinoma, Kidney, Thyroid tumour metastasis, Case report

Core Tip: This is only the third published report combined with a thyroid tumor biopsy to confirm that thyroid follicular renal cell carcinoma is not thyroid related. In addition to the typical pathologic features of this tumor, our patient had radiographic features that were different from those previously reported.