Retrospective Study
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatry. Aug 19, 2025; 15(8): 108704
Published online Aug 19, 2025. doi: 10.5498/wjp.v15.i8.108704
Association between anxiety-depression status and psychological resilience in patients with Parkinson’s disease: A risk factor analysis
Yu-Xiang Cai, Yan-Jin Wang, Jian Liu
Yu-Xiang Cai, Yan-Jin Wang, Jian Liu, Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, China
Author contributions: Cai YX designed the research and wrote the first manuscript; Cai YX, Wang YJ and Liu J contributed to conceiving the research and analyzing data; Cai YX and Liu J conducted the analysis and provided guidance for the research; all authors reviewed and approved the final manuscript.
Institutional review board statement: This study was approved by the Ethic Committee of Xiangya Hospital, Central South University.
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: All the authors declare that they have no conflict of interest.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jian Liu, MD, Department of Neurosurgery, Xiangya Hospital, Central South University, No. 87 Xiangya Road, Changsha 410008, Hunan Province, China. doclj2015@163.com
Received: April 30, 2025
Revised: June 3, 2025
Accepted: June 19, 2025
Published online: August 19, 2025
Processing time: 100 Days and 2.4 Hours
Core Tip

Core Tip: Current research on the relationship between anxiety-depression states and psychological resilience in patients with Parkinson’s disease (PD) remains limited, particularly regarding a comprehensive analysis of associated risk factors. This study identified a significant inverse relationship between the severity of anxiety and depression symptoms and the levels of psychological resilience in patients with PD. Furthermore, several key factors were found to significantly inhibit psychological resilience, including a high comorbidity burden, socioeconomic disadvantages (specifically low income and limited educational attainment), and severe emotional symptoms, as assessed using the Beck Anxiety Inventory and Geriatric Depression Scale scores.