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World J Gastrointest Pharmacol Ther. Feb 6, 2010; 1(1): 36-39
Published online Feb 6, 2010. doi: 10.4292/wjgpt.v1.i1.36
Published online Feb 6, 2010. doi: 10.4292/wjgpt.v1.i1.36
Celiac disease: Alternatives to a gluten free diet
Fabiana Zingone, Pietro Capone, Carolina Ciacci, Department of Clinical and Experimental Medicine, Federico II University, 80131 Naples, Italy
Author contributions: All of the authors participated in performing the bibliographic research and drafting the article.
Correspondence to: Carolina Ciacci, MD, Department of Clinical and Experimental Medicine, Federico II University, Via Sergio Pansini 5, 80131 Naples, Italy. ciacci@unina.it
Telephone: +39-81-7464270 Fax:+39-81-7464270
Received: November 3, 2009
Revised: December 2, 2009
Accepted: December 9, 2009
Published online: February 6, 2010
Revised: December 2, 2009
Accepted: December 9, 2009
Published online: February 6, 2010
Abstract
Celiac disease is a chronic inflammatory disorder of the small intestine caused by the ingestion of gluten or related rye and barley proteins. At present, the only available treatment is a strict gluten-exclusion diet. However, recent understanding of the molecular basis for this disorder has improved and enabled the identification of targets for new therapies. This article aims to critically summarize these recent studies.
Keywords: Celiac disease, Gluten free diet, Therapeutic options