Retrospective Study
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Sep 15, 2023; 14(9): 1412-1421
Published online Sep 15, 2023. doi: 10.4239/wjd.v14.i9.1412
Effect of sitagliptin combined with Yiqi yangyin huoxue decoction on clinical efficacy and hemorheology in early diabetic nephropathy
Jun Ling, Yan-Hua Yang
Jun Ling, Yan-Hua Yang, Department of Pharmacy, Changzhou Geriatric Hospital Affiliated to Soochow University, Changzhou NO. 7 People’s Hospital, Changzhou 213000, Jiangsu Province, China
Author contributions: This article was written by Ling J, who independently completed the research design and data analysis; and Yang YH provided important guidance for solving difficult and complex problems.
Institutional review board statement: The study was reviewed and approved by the Biomedical Research Ethics Committee, Changzhou NO. 7 People's Hospital.
Informed consent statement: This is a retrospective study and has applied for exemption from informed consent.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: Data used in this study were obtained from the corresponding author at
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Yan-Hua Yang, MM, Associate Chief Physician, Department of Pharmacy, Changzhou Geriatric Hospital Affiliated to Soochow University, Changzhou NO. 7 People’s Hospital, No. 288 Yanling East Road, Economic Development Zone, Changzhou 213000, Jiangsu Province, China.
Received: July 4, 2023
Peer-review started: July 4, 2023
First decision: July 19, 2023
Revised: July 27, 2023
Accepted: August 7, 2023
Article in press: August 7, 2023
Published online: September 15, 2023
Core Tip

Core Tip: Early diabetic nephropathy (DN) mainly involves kidney microvessels and glomerular functions, and its timely and effective treatment is critical. In clinical practice, the overall treatment effect of medication alone is not ideal. The development of traditional Chinese medicine has demonstrated its superiority for the treatment of many diseases. In the present study, sitagliptin tablets combined with a blood decoction were used to treat patients with early DN. The results showed that sitagliptin combined with Yiqi yangyin huoxue decoction had a significant effect on the treatment of early DN, which was helpful in improving hemorheological indices.