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©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Sep 15, 2023; 14(9): 1393-1402
Published online Sep 15, 2023. doi: 10.4239/wjd.v14.i9.1393
Published online Sep 15, 2023. doi: 10.4239/wjd.v14.i9.1393
Early neonatal complications in pregnant women with gestational diabetes mellitus and the effects of glycemic control on neonatal infection
Bei-Bei Wang, Mei Xue, Department of Neonatal Intensive Care Unit, Taizhou People’s Hospital of Jiangsu Province, Taizhou 225300, Jiangsu Province, China
Author contributions: Wang BB conceived the study; Wang BB and Xue M performed the data collection and extraction and analyzed the data; Wang BB and Xue M interpreted and reviewed the data and drafts; Xue M reviewed the final draft.
Institutional review board statement: The study was reviewed and approved by the Taizhou People’s Hospital of Jiangsu Province Institutional Review Board.
Informed consent statement: The analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent. According to institutional policy, this study was exempt from the informed consent process.
Conflict-of-interest statement: The authors declare no conflicts of interest for this article.
Data sharing statement: statement: The dataset is available from the corresponding author at xuemei009260@163.com .
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Mei Xue, MM, Chief Physician, Department of Neonatal Intensive Care Unit, Taizhou People’s Hospital of Jiangsu Province, No. 399 Hailing South Road, Hailing District, Taizhou 225300, Jiangsu Province, China. xuemei009260@163.com
Received: May 6, 2023
Peer-review started: May 6, 2023
First decision: May 19, 2023
Revised: May 24, 2023
Accepted: August 4, 2023
Article in press: August 4, 2023
Published online: September 15, 2023
Peer-review started: May 6, 2023
First decision: May 19, 2023
Revised: May 24, 2023
Accepted: August 4, 2023
Article in press: August 4, 2023
Published online: September 15, 2023
Core Tip
Core Tip: Gestational diabetes mellitus (GDM) is an important complication that affects pregnancy outcome. Pregnant women with GDM and long-term abnormal glucose metabolism are closely associated with the risk of adverse maternal and neonatal outcomes. Some studies suggest that the immune function of newborns may be significantly affected by GDM, and that the effect of glycemic control is related to pregnancy outcomes and neonatal prognosis. In this study, we confirmed that the risk of neonatal complications increased in pregnant women with GDM, and poor glycemic control leads to impairment of fetal immune system and ultimately increases the risk of neonatal infections.