Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Nov 15, 2022; 13(11): 940-948
Published online Nov 15, 2022. doi: 10.4239/wjd.v13.i11.940
Nutritional supplementation on wound healing in diabetic foot: What is known and what is new?
Andrea Da Porto, Cesare Miranda, Gabriele Brosolo, Giorgio Zanette, Andrea Michelli, Roberto Da Ros
Andrea Da Porto, Gabriele Brosolo, Department on Internal Medicine, University of Udine, Udine 33100, Italy
Cesare Miranda, Giorgio Zanette, Department of Internal Medicine, Clinic of Endocrinology and Metabolism Diseases Azienda Sanitaria Friuli Occidentale, Pordenone 33170, Italy
Andrea Michelli, Roberto Da Ros, Department of Internal Medicine , SC Diabete e Centro Trattamento Piede Diabetico, Monfalcone 34074, Gorizia, Italy
Author contributions: Da Porto A and Miranda C came up with ideas and constructs; Da Porto A, Miranda C, and Da Ros R wrote the manuscript; Michelli A, Brosolo G, and Zanette G approved the main conceptual ideas and made corrections; all authors provided final edits and approved the manuscript.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Andrea Da Porto, MD, MSc, Doctor, Department on Internal Medicine, University of Udine, Via Colugna, Udine 33100, Italy.
Received: August 11, 2022
Peer-review started: August 11, 2022
First decision: September 4, 2022
Revised: September 13, 2022
Accepted: October 11, 2022
Article in press: October 11, 2022
Published online: November 15, 2022
Core Tip

Core Tip: Malnutrition is common in patients with diabetes and chronic wounds. To date we do not have clear recommendations or evidence about the use of nutritional supplements for improving wound healing in patients with diabetic foot ulcers (DFU). This paper aimed to evaluate current evidence regarding the use of Nutritional supplementation on wound healing in patients with DFU.