Circular RNA hsa_circRNA_101996 modulates gastric cancer cell proliferation and apoptosis through the miR-577/HMGN5 axis

Table 1 Sequence of primers

Name	Forward/sense (from 5’ to 3’)	Reverse/antisense (from 5’ to 3’)
circRNA_101996	GAGTGGGAGTGTTGGAAGAAG	TTACTAAAGGCAAACGGTGAA
miR-577	GCGGCGGTAGATAAAATATTGG	ATCCAGTGCAGGGTCCGAGG
HMGN5	GGTTGTCTGCTATGCTTGTG	ACTGCTTCTTGCTTGGTTTC
GAPDH	GGAGAGTGTTTCCTCGTCCC	ACTGTGCCGTTGAATTTGCC
U6	GCGCGTCGTGAAGCGTTC	GTGCAGGGTCCGAGGT

Table 2 The correlation between hsa_circRNA_101996/miR-577/HMGN5 level in gastric cancer tissue and the clinical characteristics of patients, n

Clinical characteristics	hsa_circRNA_101996			miR-577			HMGN5
	Low expression group (≤ median)	High expression group (> median)	P value	Low expression group (≤ median)	High expression group (> median)	P value	Low expression group (≤ median)	High expression group (> median)	P value
Gender			0.443			0.890			0.162
Male	8	10		9	9		7	11
Female	13	10		12	11		14	9
Age			0.890			0.262			0.443
> 50	12	11		10	13		13	10
≤ 50	9	9		11	7		8	10
Body mass index (kg/m2)			0.837			0.393			0.275
> 24	13	13		12	14		15	11
≤ 24	8	7		9	6		6	9
Tumor size (cm)			< 0.001			0.043			0.003
> 3	5	16		14	7		6	15
≤ 3	16	4		7	13		15	5
TNM stage			0.654			0.086			0.412
1-2	8	9		6	11		10	7
3-4	13	11		15	9		11	13