Case Report
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. May 15, 2025; 17(5): 105417
Published online May 15, 2025. doi: 10.4251/wjgo.v17.i5.105417
Mucinous cystic neoplasm mimicking pancreatic pseudocyst and progressing to adenocarcinoma: A case report
Zhi-Yu Yan, Wen Shi, Tao Guo, Ai-Ming Yang
Zhi-Yu Yan, Wen Shi, Tao Guo, Ai-Ming Yang, Department of Gastroenterology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 100730, China
Zhi-Yu Yan, Department of Internal Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China
Author contributions: Yan ZY, Shi W, and Guo T contributed to the study conceptualization; Guo T and Yang AM supervised the study; Yan ZY contributed to data collection and manuscript drafting; Shi W and Guo T contributed to manuscript revision; and all authors have approved the final manuscript.
Supported by the National Key Research and Development Program of China, ‘Clinical Performance Verification of Radial Ultrasound Endoscope’, No. 2017YFC0109804; and the National High Level Hospital Clinical Research Funding, No. 2022-PUMCH-A-076.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Tao Guo, MD, Professor, Department of Gastroenterology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, No. 1 Shuaifuyuan Wangfujing, Dongcheng District, Beijing 100730, China. guoqiong990@126.com
Received: January 27, 2025
Revised: March 22, 2025
Accepted: April 22, 2025
Published online: May 15, 2025
Processing time: 110 Days and 20.3 Hours
Core Tip

Core Tip: Advances in imaging are resulting in more incidental diagnoses of pancreatic cystic lesions. However, they can be challenging to subclassify, and their malignant potential varies, requiring different treatment approaches. Endoscopic ultrasound and ancillary methods like fine-needle aspiration and needle-based confocal laser endomicroscopy are significantly improving the sensitivity and accuracy of diagnosis. However, in this case, all these methods failed to identify subsequent malignant transformation, emphasizing the importance of attention to detail and strict and close surveillance where clinical uncertainty exists.