Thrombocytopenia in cirrhosis: Impact of fibrinogen on bleeding risk
Sonali V Thakrar, Susan V Mallett, Royal Free Perioperative Research Group, Department of Anaesthesia, Royal Free London, London NW3 2QG, United Kingdom
Author contributions: Thakrar SV and Mallett SV contributed equally to this work in designed and coordinated the research and writing the manuscript.
Institutional review board statement: This work was reviewed and approved by the Royal Free London Research and Development department and was deemed not to require ethics approval.
Informed consent statement: All data retrieved from our transplant database was anonymised. The data has been previously collected (prior to the study commencing), and was collected as part of standard care. Only those persons involved in clinical care had access to our database. No patient interventions were performed as part of this study. As a result, it was deemed unnecessary to require patient consent.
Conflict-of-interest statement: There are no conflicts of interest to declare.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at firstname.lastname@example.org. Participant onsent was not obtained but the presented data are anonymised and risk of identification is low.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Sonali V Thakrar, MBBS, BSc (Hons), MRCP, FRCA, Clinical Research Fellow, Royal Free Perioperative Research Group, Department of Anaesthesia, Royal Free London, Pond Street, London NW3 2QG, United Kingdom. email@example.com
Received: July 27, 2016
Peer-review started: July 29, 2016
First decision: September 28, 2016
Revised: December 23, 2016
Accepted: January 11, 2017
Article in press: January 14, 2017
Published online: February 28, 2017