Original Articles
Copyright ©The Author(s) 1998.
World J Gastroenterol. Jun 15, 1998; 4(3): 210-213
Published online Jun 15, 1998. doi: 10.3748/wjg.v4.i3.210
Table 1 Secretion of IFN-γ and expression of HLA antigens by transduced hepatocellular carcinoma cells in culture
Cell linesIFN-γ ProductionControl*HLA class I * *HLA class II
(U/5 × 105 cells/24 h)MCN (% positive)△△MCN (% positive)MCN (% positive)
QGY7701018 (6)159 (99)26 (11)
QGY7701.3A7521 (5)306 (100)28 (77)
SMMC772109 (2)200 (100)13 (12)
SMMC7721.2C15021 (3)348 (100)14 (58)
BEL7704020 (7)34 (93)21 (8)
BEL7404.6A7522 (5)117 (100)29 (47)
HHCL010 (3)232 (100)12 (10)
HHCL.2C10022 (6)340 (100)37 (56)
HHCL.2D2514 (6)440 (100)12 (68)
HHCL.5C10011 (4)401 (100)19 (83)
HHCL.6C7515 (3)550 (100)10 (44)
HHCL.5D20010 (3)341 (100)10 (40)
Table 2 Formation of tumors by parental and transduced hepatocellular carcinoma cells in nude mice
CellIncidenceVolume (cm3)Weight (g)
QGY77018/85.58 ± 0.901.62 ± 0.36
QGY7701.3A8/85.16 ± 161.60 ± 0.72
SMMC77217/73.87 ± 0.240.55 ± 0.12S
MMC7721.2C5/61.26 ± 0.32a0.28 ± 0.08a
BEL74048/84.32 ± 0.280.78 ± 0.14
BEL7404.6A8/83.35 ± 0.210.50 ± 0.12
HHCL8/82.04 ± 0.320.35 ± 0.18
HHCL.5D1/70.15b0.02b