Portolani N, Baiocchi GL, Gadaldi S, Fisogni S, Villanacci V. Dysplasia in perforated intestinal pneumatosis complicating a previous jejuno-ileal bypass: A cautionary note. World J Gastroenterol 2009; 15(33): 4189-4192
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Dr. Gian Luca Baiocchi, Department of Medical and Surgical Sciences, Surgical Clinic, Brescia University, Via Cicognini, 6, 25127 Brescia, Italy. firstname.lastname@example.org
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Nazario Portolani, Gian Luca Baiocchi, Stefano Gadaldi, Department of Medical and Surgical Sciences, Surgical Clinic, Brescia University, 25127 Brescia, Italy
Simona Fisogni, Vincenzo Villanacci, 2nd Department of Pathology, Spedali Civili, I-25100 Brescia, Italy
Author contributions: Portolani N and Baiocchi GL designed research; Gadaldi S performed research; Fisogni S and Villanacci V performed the histopathological analysis; Portolani N and Baiocchi GL wrote the paper.
Correspondence to: Dr. Gian Luca Baiocchi, Department of Medical and Surgical Sciences, Surgical Clinic, Brescia University, Via Cicognini, 6, 25127 Brescia, Italy. email@example.com
Telephone: +39-30-3397476 Fax: +39-30-3397476
Received: July 31, 2009 Revised: August 4, 2009 Accepted: August 11, 2009 Published online: September 7, 2009
We present the case of an elderly woman who developed a bowel perforation related to pneumatosis intestinalis, 33 years after a jejuno-ileal bypass for severe obesity. Final histological examination revealed the presence of dysplasia in the resected specimen. On the basis of our case and a review of the literature, we discuss the etiopathogenesis, the clinical aspects and the treatment of this rare condition.