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©The Author(s) 2005. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Aug 7, 2005; 11(29): 4604-4606
Published online Aug 7, 2005. doi: 10.3748/wjg.v11.i29.4604
Published online Aug 7, 2005. doi: 10.3748/wjg.v11.i29.4604
Alterations of serum cholinesterase in patients with gastric cancer
Shan-Zhi Gu, Xin-Han Zhao, Ping Quan, Sheng-Bin Li, Key Laboratory of Environment and Genes Related to Diseases of Ministry of Education , Medical College of Xi’an Jiaotong University, Xi’an 710061, Shaanxi Province, China
Bo-Rong Pan, Department of Oncology, Xijing Hospital, Fourth Military Medical University, Xi’an 710032, Shaanxi Province, China
Author contributions: All authors contributed equally to the work.
Correspondence to: Xin-Han Zhao, Key Laboratory of Environment and Genes Related to Diseases of Ministry of Education, Department of Medical Oncology, First Hospital of Xi’an Jiaotong University, Xi’an 710061, Shaanxi Province, China. zhxinhan@pub.xaonline.com
Telephone: +86-29-85324136 Fax:+86-29-82655472
Received: October 9, 2004
Revised: November 23, 2004
Accepted: November 26, 2004
Published online: August 7, 2005
Revised: November 23, 2004
Accepted: November 26, 2004
Published online: August 7, 2005
Abstract
AIM: To understand the correlation of serum cholinesterase (CHE) activity with gastric cancer and to assess their clinical significance.
METHODS: The velocity method was adopted to detect the activity of serum CHE in patients with gastric cancer and in patients with non-malignant tumor as controls.
RESULTS: The serum CHE activity in the treatment group was significantly lower than that in the control group with a very significant difference between the two groups (83.3:113.1,P = 0.0003). Age was significantly associated with the incidence of gastric caner.
CONCLUSION: Serum CHE activity has a close relation with the incidence of gastric cancer.
Keywords: Cholinesterase activity, Gastric cancer