Impact of frailty on outcomes of elderly patients undergoing percutaneous coronary intervention: A systematic review and meta-analysis

Table 4 Subgroup analysis for all-cause mortality

Criteria	Subgroup	HR (95%CI)	P value	I2 (%)
Overall		2.08 (1.78-2.43)	< 0.0001	98
Study design	Prospective	2.70 (1.78-2.43)	< 0.0001	98
	Retrospective	2.45 (1.51-3.98)	0.0003	90
Age	< 75 yr	2.24 (1.15-3.25)	< 0.0001	98
	> 75 yr	3.58 (1.29-9.94)	0.01	94
Frailty scale	CFS	3.89 (1.88-8.05)	0.0003	86
	Others	1.82 (1.53-2.17)	< 0.0001	99
Patients for PCI	CAD	1.74 (1.50-2.30)	< 0.0001	98
	STEMI	3.48 (2.00-6.03)	< 0.0001	64

CFS: Clinical Frailty Scale; CAD: Coronary artery disease; PCI: Percutaneous coronary intervention; HR: Hazard ratio; 95%CI: 95% confidence interval.