Efficacy and safety of propofol target-controlled infusion combined with butorphanol for sedated colonoscopy

Table 2 Comparison of median effective concentration, dose for anesthesia, and awakening concentration of propofol among the different groups

Groups	n	EC50 (μg/mL)	95%CI (μg/mL)	Amount of propofol necessary for anesthesia (mg)	Awakening concentration of propofol (μg/mL)
Group C	38	4.05	3.78-4.34	151.0 (142.0-160.5)	1.200 (0.975-1.300)
Group B1	36	3.411	3.20-3.62	142 (135-154)1,3	1.200 (1.025-1.500)3
Group B2	32	3.031,2	2.83-3.23	132.00 (125.00-144.75)1,2	1.1 (0.9-1.2)2

¹P < 0.05 vs the control group (group C).

²P < 0.05 vs group B1.

³P < 0.05 vs group B2.

Awakening concentration of propofol was defined as the effect-site concentration of propofol in association with eye opening in response to verbal command. CI: Confidence interval; EC50: Effective concentration