Malignant solitary fibrous tumor of the pancreas with systemic metastasis: A case report and review of the literature

Figure 1 Computed tomography imaging of the abdomen. A: A 4.7 cm × 4.4 cm mass (white arrow) located in the body of pancreas. Non-uniform enhancement was observed from the arterial phase [computed tomography (CT) value = 68 Hu] to portal venous phase (CT value = 59 Hu); B: Numerous liver metastatic tumors (white arrows). Enhanced scanning showed irregular enhancement and the largest one located in segment VIII measured 15.9 cm.

Figure 2 Systemic fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography scan. The positron emission tomography/computed tomography scan revealed an increased uptake of fluorodeoxyglucose in the liver and heterogeneous fluorodeoxyglucose uptake in multiple bones.

Figure 3 Photographs of cut surface of surgical specimens. A: A soft mass located in the body of pancreas. Hemorrhage and necrosis changes can be seen in the cut surface; B: The pale-yellow cut surface of the hepatic metastasis.

Figure 4 Photomicrographs of histologic and immunohistochemical staining. A: Various atypical spindled cells irregularly arranged in the stroma [hematoxylin-eosin (HE) staining; magnification: ×50]; B: Histologic demonstration of mitotic activity (HE staining; magnification: ×200); C: Presence of necrosis (HE staining; magnification: ×100); D: Immunohistochemical staining for STAT6 showed diffused positivity in tumor cells (magnification: ×100).

Figure 5 Timeline. A brief summary of the patient’s medical history is presented. TACE: Transcatheter arterial chemoembolization.