Case Report
Copyright ©The Author(s) 2020.
World J Clin Cases. Oct 6, 2020; 8(19): 4579-4587
Published online Oct 6, 2020. doi: 10.12998/wjcc.v8.i19.4579
Figure 1
Figure 1 Microscopic examination of peripheral blood and bone marrow. A: PB showed rouleaux formation of red blood cells and an atypical promyelocyte; B: BM aspiration smears showed increased number of atypical promyelocytes with bilobed nuclei and densely packed large granules in the cytoplasm (Wright-Giemsa staining, × 1000). PB: Peripheral blood; BM: Bone marrow.
Figure 2
Figure 2 Flow cytometric immunophenotyping showing that the bone marrow expressed CD13, CD33, CD117, CD56, CD81, and myeloperoxidase; partially expressed CD38 and CD34; and slightly expressed CD15, CD11b, and CD16.
Figure 3
Figure 3 Cytogenetic analysis. G-band karyotyping of bone marrow cells revealed 46, XX, t(15; 17) (q22; q21).
Figure 4
Figure 4 Sanger sequencing results indicating a positive FMS-like tyrosine kinase 3-internal tandem duplication mutation (the orange arrow indicates the mutation site).