Mixed neuroendocrine-nonneuroendocrine neoplasm of the ampulla: Four case reports

Figure 1 Enhanced computed tomography of the abdomen of patient 4. A: The ampullary mass shown by the orange arrow protrudes into the duodenal cavity, and the arterial phase shows uneven enhancement; B: The tumor caused significant dilation of the bile ducts and pancreatic ducts inside and outside the liver; C: Postoperative liver metastases indicated by orange arrows.

Figure 2 Enhanced magnetic resonance imaging of the abdomen and duodenoscopy of patient 3. A: The orange arrow shows an oval mass in the ampulla, which shows high signal intensity on diffusion weighted imaging and the boundary is still clear; B: After the mass is enhanced, it shows uneven ring enhancement; C: An irregular ulcer in the ampulla was seen under the endoscopy, with a crater-like bulge around it.

Figure 3 Light microscope images of hematoxylin-eosin stained lesion sections of 4 patients. Original magnification: × 200.

Figure 4 Light microscope image with immunohistochemical staining. A: CD56+; B: CgA+; C: Syn+. Original magnification: × 200.