Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Mar 16, 2021; 9(8): 1863-1870
Published online Mar 16, 2021. doi: 10.12998/wjcc.v9.i8.1863
Intradural osteomas: Report of two cases
Li Li, Guang-Yu Ying, Ya-Juan Tang, Hemmings Wu
Li Li, Guang-Yu Ying, Ya-Juan Tang, Hemmings Wu, Department of Neurosurgery, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, Zhejiang Province, China
Author contributions: Li L, Ying GY, and Tang YJ participated in the diagnosis and management of this case; Li L wrote the manuscript; Wu H revised the manuscript for important intellectual content; all authors read and approved the final manuscript.
Supported by Zhejiang Medicine and Health Science and Technology Project, No. 2017KY072.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors declare having no conflicts of interest in relation to these cases and their treatment or publication.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Li Li, MD, Doctor, Research Fellow, Surgeon, Department of Neurosurgery, The Second Affiliated Hospital of Zhejiang University School of Medicine, No. 88 Jiefang Road, Hangzhou 310009, Zhejiang Province, China. touchspark@zju.edu.cn
Received: August 30, 2020
Peer-review started: August 30, 2020
First decision: December 21, 2020
Revised: January 3, 2021
Accepted: January 20, 2021
Article in press: January 20, 2021
Published online: March 16, 2021
Core Tip

Core Tip: Intradural osteoma is very rarely located in the subdural or subarachnoid space; although, there are disease associations related to sex, ethnicity, and intracranial locations. Intradural osteomas usually require surgery and pathological examination for diagnosis, and craniotomy is considered a safe and effective treatment. In this paper, we describe two cases of intradural osteomas located in the subdural and subarachnoid spaces, respectively, and provide a review of the related literature. The neural crest cell hypothesis is proposed to explain the pathogenesis of this rare tumor localization.