Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jun 26, 2021; 9(18): 4823-4828
Published online Jun 26, 2021. doi: 10.12998/wjcc.v9.i18.4823
Anderson-Fabry disease presenting with atrial fibrillation as earlier sign in a young patient: A case report
Hangyul Kim, Min Gyu Kang, Hyun Woong Park, Jeong-Rang Park, Jin-Yong Hwang, Kyehwan Kim
Hangyul Kim, Min Gyu Kang, Hyun Woong Park, Kyehwan Kim, Department of Internal Medicine, Gyeongsang National University Hospital, Jinju 52727, South Korea
Jeong-Rang Park, Jin-Yong Hwang, Department of Internal Medicine, Gyeongsang National University School of Medicine and Gyeongsang National University Hospital, Jinju 52727, South Korea
Author contributions: Park JR was the patient’s cardiologist, reviewed the literature and contributed to manuscript drafting; Kim H and Kim K reviewed the literature and contributed to manuscript drafting; Kang MG and Park HW performed the interpretation of clinical findings and electrocardiography and contributed to manuscript drafting; Park JR who is an expert in the echocardiography and cardiologist analyzed and interpreted the echocardiographic imaging findings; Hwang JY performed the treatment strategy and diagnosis for Anderson-Fabry disease consultation, reviewed the literature and drafted the manuscript; Kim K and Kim H were responsible for the revision of the manuscript for important intellectual content; and all authors issued final approval for the version to be submitted.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Kyehwan Kim, MD, Assistant Professor, Doctor, Department of Internal Medicine, Gyeongsang National University Hospital, 79, Gangnam-ro, Gyeongsangnam-do, Jinju 52727, South Korea. nicol2000@nate.com
Received: January 28, 2021
Peer-review started: January 28, 2021
First decision: February 25, 2021
Revised: March 3, 2021
Accepted: May 15, 2021
Article in press: May 15, 2021
Published online: June 26, 2021
Core Tip

Core Tip: Atrial fibrillation as the initial presenting sign at a young age is rare. It was essential to identify the cause of the atrial fibrillation and hypertrophic myocardium with no history of hypertension in the young patient. Even though atrial fibrillation was incidentally converted into sinus rhythm, the restored rhythm clarified the shortened PR interval and segment without delta wave, which became a crucial clue for Anderson-Fabry disease (AFD) diagnosis. Therefore, sinus conversion to detect the relationship between P and QRS may be needed and helpful in differential diagnoses such as AFD and other heart diseases.