Case Report
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Apr 6, 2020; 8(7): 1287-1294
Published online Apr 6, 2020. doi: 10.12998/wjcc.v8.i7.1287
Scaphoid metastasis as the first sign of occult gastroesophageal junction cancer: A case report
Yu-Jie Zhang, Yan-Yan Wang, Qi Yang, Jian-Bing Li
Yu-Jie Zhang, Jian-Bing Li, Department of Orthopedic Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, Zhejiang Province, China
Yan-Yan Wang, Department of Oncology Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, Zhejiang Province, China
Qi Yang, Department of Pathology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, Zhejiang Province, China
Author contributions: Zhang YJ and Li JB were the patient’s orthopedists, reviewed the literature, and wrote the manuscript; Wang YY and Yang Q were responsible for providing professional guidance and collecting the medical imaging materials; Li JB revised the manuscript; all authors issued final approval for the version to be submitted.
Supported by Natural Science Foundation of Zhejiang Province, No. LQ19H060002 and No. LQ19H160041; Medical and Health Science and Technology Project of Zhejiang Province, No. 2018KY089.
Informed consent statement: Written informed consent was obtained from the patient and his wife for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016)
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Jian-Bing Li, MD, Doctor, Department of Orthopedic Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou 310009, Zhejiang Province, China. 2505002@zju.edu.cn
Received: December 20, 2019
Peer-review started: December 20, 2019
First decision: January 7, 2020
Revised: January 13, 2020
Accepted: March 9, 2020
Article in press: March 9, 2020
Published online: April 6, 2020
Core Tip

Core tip: Hand metastasis is very rare, especially when it is the first sign of an occult primary malignancy. Here, we report a case of a scaphoid bone lesion that had metastasized from a gastroesophageal junction adenocarcinoma; the initial manifestation was persistent wrist pain and swelling. Due to its low incidence and the lack of specific symptoms, hand bone metastasis is easily misdiagnosed, leading to delayed treatment. A review of the literature provides a systematic understanding of the epidemiology, manifestations, diagnosis, treatment, and prognosis of metastatic carcinomas of the hand. Moreover, the early detection and diagnosis of hand metastasis are needed to improve patients’ quality of life and prolong their survival.