Case Report
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Mar 6, 2020; 8(5): 922-927
Published online Mar 6, 2020. doi: 10.12998/wjcc.v8.i5.922
Oxcarbazepine for trigeminal neuralgia may induce lower extremity weakness: A case report
Hyun-Gul Song, Francis Sahngun Nahm
Hyun-Gul Song, Department of Anesthesiology and Pain Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul 07061, South Korea
Francis Sahngun Nahm, Department of Anesthesiology and Pain Medicine, Seoul National University Bundang Hospital, Seongnam 13620, South Korea
Author contributions: Song HG contributed to Conceptualization/Original draft; Nahm FS contributed to Supervision/Review and editing.
Informed consent statement: Written informed consent was obtained from the patient for publication. This case report was approved by the Institutional Review Board of the SMG-SNU Boramae Medical Center.
Conflict-of-interest statement: The authors declare no conflicts of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Francis Sahngun Nahm, MD, PhD, Associate Professor, Department of Anesthesiology and Pain Medicine, Seoul National University Bundang Hospital, 82 Gumi-ro 173 Beon-gil, Bundang-gu, Seongnam 13620, South Korea.
Received: December 3, 2019
Peer-review started: December 3, 2019
First decision: January 7, 2020
Revised: February 4, 2020
Accepted: February 12, 2020
Article in press: February 12, 2020
Published online: March 6, 2020
Processing time: 93 Days and 20.8 Hours
Core Tip

Core tip: Unsteady gait is a rare complication of oxcarbazepine; only few cases have been reported and most patients reported in case reports have epilepsy, not neuropathic pain. Oxcarbazepine, along with carbamazepine, is a commonly used drug for the first-line treatment for trigeminal neuralgia. Herein, we report the case of a patient with spinal stenosis who was on long-term oxcarbazepine therapy for trigeminal neuralgia, and manifested symptoms of lower leg weakness as a complication to medication rather than spinal stenosis.