Case Report
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Oct 6, 2020; 8(19): 4488-4493
Published online Oct 6, 2020. doi: 10.12998/wjcc.v8.i19.4488
Extremely rare case of successful treatment of metastatic ovarian undifferentiated carcinoma with high-dose combination cytotoxic chemotherapy: A case report
Hong Beum Kim, Hee Jeong Lee, Ran Hong, Sang-Gon Park
Hong Beum Kim, Department of Premedical Course, Chosun University School of Medicine, Gwngju 505717, South Korea
Hee Jeong Lee, Sang-Gon Park, Department of Internal Medicine, Hemato-oncology, Chosun University Hospital, Gwangju 505717, South Korea
Ran Hong, Department of Pathology, Chosun University Hospital, Gwangju 505717, South Korea
Author contributions: Kim HB contributed to manuscript drafting; Hong R confirmed the pathology; Park SG advised manuscript drafting; Lee HJ proofread and revised the manuscript as a corresponding author; all authors issued final approval for the version to be submitted.
Supported by the National Research Foundation of Korea, funded by the Ministry of Science, ICT, and Future Planning, No. NRF-2017R1D1A1B04031741; and grants from the Chosun University Hospital, No. 2019.
Informed consent statement: Written informed consent was obtained from the patient for publication of this case report and any accompanying images.
Conflict-of-interest statement: The authors declare no conflict-of-interest.
CARE Checklist (2016) statement: The manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Hee Jeong Lee, MD, PhD, Assistant Professor, Doctor, Department of Internal Medicine, Hemato-oncology, Chosun University Hospital, 365 Pilmun-daero, Dong-gu, Gwang-ju 505717, South Korea. hjangel21c@hanmail.net
Received: March 3, 2020
Peer-review started: March 3, 2020
First decision: July 25, 2020
Revised: August 9, 2020
Accepted: September 2, 2020
Article in press: September 2, 2020
Published online: October 6, 2020
Processing time: 208 Days and 23.4 Hours
Core Tip

Core Tip: Palliative chemotherapy is the only available treatment for metastatic ovarian undifferentiated carcinoma. However, we used a high-dose combination chemotherapy of etoposide, ifosfamide, and cisplatin instead of the widely used paclitaxel and platinum and successfully treated an extremely rare case of inoperable metastatic ovarian undifferentiated carcinoma.