Letter To The Editor
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jun 6, 2020; 8(11): 2406-2407
Published online Jun 6, 2020. doi: 10.12998/wjcc.v8.i11.2406
Macrophage activation syndrome as an initial presentation of systemic lupus erythematosus
Lian-Jie Shi, Qian Guo, Sheng-Guang Li
Lian-Jie Shi, Qian Guo, Sheng-Guang Li, Department of Rheumatology and Immunology, Peking University International Hospital, Beijing 102206, China
Author contributions: Shi LJ and Guo Q contributed equally to this work; Shi LJ and Guo Q performed literature search and wrote the letter; Li SG performed critical comments.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Sheng-Guang Li, MD, Professor, Department of Rheumatology and Immunology, Peking University International Hospital, No. 1, Life Park Road, Life Science Park of Zhongguancun, Changping District, Beijing 102206, China. lishengguang@pkuih.edu.cn
Received: January 15, 2020
Peer-review started: January 15, 2020
First decision: April 24, 2020
Revised: May 5, 2020
Accepted: May 13, 2020
Article in press: May 13, 2020
Published online: June 6, 2020
Core Tip

Core tip: The recent report (World J Clin Cases 2019; 7: 3859-3865) about a 36-year-old female with macrophage activity syndrome as an onset of systemic lupus erythematosus was rare and interesting. However, the presented patient diagnosed with macrophage activity syndrome should have a high inflammatory status, but reported a normal C-reactive protein level. Furthermore, the medical information on the patient was inadequate for a diagnosis of systemic lupus erythematosus. Therefore, a profound discussion needs to be addressed.