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©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Mar 6, 2019; 7(5): 572-584
Published online Mar 6, 2019. doi: 10.12998/wjcc.v7.i5.572
Published online Mar 6, 2019. doi: 10.12998/wjcc.v7.i5.572
Adiponectin gene polymorphisms and risk of gestational diabetes mellitus: A meta-analysis
Lin-Ting Huang, Shi-Lan Wu, Xin Liao, Shu-Juan Ma, Hong-Zhuan Tan, Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha 410083, Hunan Province, China
Author contributions: Huang LT conceived the study, acquired, analyzed, and interpreted the data, and drafted the manuscript; Wu SL and Xin L acquired, analyzed, and interpreted the data and revised the manuscript; Ma SJ interpreted the data and revised the manuscript; Tan HZ conceived and designed the study and critically revised the manuscript. All author approved the final version of the manuscript.
Supported by the National Nature Science Foundation of China , No. 81773535 .
Conflict-of-interest statement: The authors deny any conflict of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Hong-Zhuan Tan, MD, PhD, Professor, Xiangya School of Public Health, Central South University, Changsha 410008, Hunan Province, China. tanhz99@qq.com
Telephone: +86-731-88858435 Fax: +86-731-84805454
Received: November 20, 2018
Peer-review started: November 21, 2018
First decision: December 15, 2018
Revised: December 24, 2018
Accepted: January 3, 2019
Article in press: January 3, 2019
Published online: March 6, 2019
Peer-review started: November 21, 2018
First decision: December 15, 2018
Revised: December 24, 2018
Accepted: January 3, 2019
Article in press: January 3, 2019
Published online: March 6, 2019
Core Tip
Core tip: No consensus is available in the literature about the association of adiponectin gene polymorphisms and the risk of gestational diabetes mellitus (GDM). As far as we know, only +45T/G was involved in a previous meta-analysis with a small sample size and obvious heterogeneity. We evaluated the association between ADIPOQ +45T/G, +276G/T, and -11377C/G polymorphisms and GDM with a bigger sample size, less heterogeneity. Moreover, subgroup analysis was performed by ethnicity.