Case Report
Copyright ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Oct 6, 2019; 7(19): 3047-3054
Published online Oct 6, 2019. doi: 10.12998/wjcc.v7.i19.3047
Severe heterotopic ossification in a seronegative spondyloarthritis patient after cervical Bryan disc arthroplasty: A case report
Chih-Wei Huang, Chien-Lun Tang, Hung-Chuan Pan, Chung-Yuh Tzeng, Hsi-Kai Tsou
Chih-Wei Huang, Chien-Lun Tang, Neurological Institute, Taichung Veterans General Hospital, Taichung 407, Taiwan
Hung-Chuan Pan, Hsi-Kai Tsou, Functional Neurosurgery Division, Neurological Institute, Taichung Veterans General Hospital, Taichung 407, Taiwan
Hung-Chuan Pan, Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei 112, Taiwan
Chung-Yuh Tzeng, Division of Joint Reconstruction, Department of Orthopedics, Taichung Veterans General Hospital, Taichung 407, Taiwan
Chung-Yuh Tzeng, Department of Medicinal Botanicals and Health Applications, Da-Yeh University, Changhua County 515, Taiwan
Hsi-Kai Tsou, Department of Rehabilitation, Jen-Teh Junior College of Medicine, Nursing and Management, Miaoli County 356, Taiwan
Author contributions: Huang CW designed and wrote the report; Tang CL reviewed the manuscript for its intellectual content and revised the entire work; Pan HC performed the analysis and evaluations; Tsou HK performed the treatment of this case; Tsou HK and Tzeng CY reviewed the manuscript for its intellectual content; all authors have read and approved the final manuscript.
Informed consent statement: The patient involved in this study gave written informed consent authorizing the use and disclosure of his protected health information.
Conflict-of-interest statement: The authors of this manuscript have no conflicts of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Hsi-Kai Tsou, MD, PhD, Chief Doctor, Professor, Functional Neurosurgery Division, Neurological Institute, Taichung Veterans General Hospital, 1650 Taiwan Boulevard Sec. 4, Taichung 407, Taiwan.
Telephone: +886-4-23741218 Fax: +886-4-23741218
Received: May 17, 2019
Peer-review started: May 23, 2019
First decision: August 1, 2019
Revised: August 20, 2019
Accepted: August 27, 2019
Article in press: August 27, 2019
Published online: October 6, 2019
Core Tip

Core tip: Severe traction spur type heterotopic ossification (HO) occurred after cervical disc arthroplasty (CDA) with Bryan discs and matured in the second year after operation. A second CDA for the adjacent segment disease herniation of the intervertebral disc with Baguera C disc over the C3-C4 level achieved excellent outcome. Based on the second operation experience, the avoidance of unnecessary soft tissue traction and trauma such as burring, milling, or keeling during the operation and the prophylactic use of non-steroidal anti-inflammatory drugs are mandatory to prevent HO formation.