Case Report
Copyright ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Aug 26, 2019; 7(16): 2309-2315
Published online Aug 26, 2019. doi: 10.12998/wjcc.v7.i16.2309
Successful treatment of tubulointerstitial nephritis in immunoglobulin G4-related disease with rituximab: A case report
Eray Eroglu, Murat Hayri Sipahioglu, Soner Senel, Sule Ketenci Ertas, Seyma Savas, Figen Ozturk, Ismail Kocyigit, Bulent Tokgoz, Oktay Oymak
Eray Eroglu, Murat Hayri Sipahioglu, Ismail Kocyigit, Bulent Tokgoz, Oktay Oymak, Division of Nephrology, Department of Internal Medicine, Erciyes University School of Medicine, Kayseri 38039, Turkey
Soner Senel, Sule Ketenci Ertas, Division of Rheumatology, Department of Internal Medicine, Erciyes University School of Medicine, Kayseri 38039, Turkey
Seyma Savas, Department of Internal Medicine, Erciyes University School of Medicine, Kayseri 38039, Turkey
Figen Ozturk, Department of Pathology, Erciyes University School of Medicine, Kayseri 38039, Turkey
Author contributions: Eroglu E, Sipahioglu MH and Oymak O designed the report; Eroglu E, Senel S, Ertas SK and Savas S collected the patient’s clinical data; Ozturk F reported the biopsy specimens; Eroglu E and Sipahoglu MH analyzed the data and wrote the paper, Kocyigit I and Tokgoz B revised the paper.
Informed consent statement: Consent was obtained from the patient at the time of investigations, but not at the time of writing case report.
Conflict-of-interest statement: All authors declared there were no conflicts of interest involved.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016) and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Eray Eroglu, MD, Research fellow, Division of Nephrology, Department of Internal Medicine, Erciyes University Medical School, Kayseri 38039, Turkey. eroglu@erciyes.edu.tr
Telephone: +90-530-9220517 Fax: +90-352-4375807
Received: April 15, 2019
Peer-review started: April 15, 2019
First decision: May 31, 2019
Revised: July 9, 2019
Accepted: July 27, 2019
Article in press: July 27, 2019
Published online: August 26, 2019
Core Tip

Core tip: Immunoglobulin G4-related disease is an immune-mediated condition that mimics several rheumatologic disorders and malignancies. The diagnosis can be provided by detecting lymphoplasmacytic infiltration with storiform fibrosis in the histopathological examination of the affected organ. However, steroid is the mainstay treatment agent, rituximab should be addressed in resistant cases.