Case Report
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Apr 6, 2024; 12(10): 1844-1850
Published online Apr 6, 2024. doi: 10.12998/wjcc.v12.i10.1844
Panhypopituitarism caused by a suprasellar germinoma: A case report
Jelena Roganovic, Lea Saric, Silvije Segulja, Ana Dordevic, Mia Radosevic
Jelena Roganovic, Department of Pediatrics, Clinical Hospital Centre Rijeka, Rijeka 51000, Croatia
Jelena Roganovic, Lea Saric, Mia Radosevic, Faculty of Medicine, University of Rijeka, Rijeka 51000, Croatia
Silvije Segulja, Faculty of Health Sciences, University of Rijeka, Rijeka 51000, Croatia
Ana Dordevic, Department of Business Development, Jadran Galenski Laboratorij, Rijeka 51000, Croatia
Author contributions: Roganovic J designed the study and oversaw patient treatment; Saric L, Dordevic A and Radosevic M collected data; Roganovic J, Saric L, Segulja S, Dordevic A and Radosevic M wrote the paper; Roganovic J was responsible for writing instructions and communication contact; and all authors have read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the parent of the patient for publication of this report and accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jelena Roganovic, PhD, Adjunct Professor, Department of Pediatrics, Clinical Hospital Centre Rijeka, Istarska 43, Rijeka 51000, Croatia. roganovic.kbcri@gmail.com
Received: January 4, 2024
Peer-review started: January 4, 2024
First decision: January 17, 2024
Revised: January 31, 2024
Accepted: March 15, 2024
Article in press: March 15, 2024
Published online: April 6, 2024
Core Tip

Core Tip: Suprasellar germinomas are rare tumors that may be associated with hypopituitarism at diagnosis and after therapy. We report the presentation, diagnosis, treatment, and complications of a suprasellar germinoma in a 12-year-old patient. The tumor caused visual impairment, headaches, and hypopituitarism. The patient was treated surgically, followed by adjuvant chemotherapy and radiotherapy. Post-treatment panhypopituitarism required hormonal replacement therapy. The case underscores the complexity of managing these rare tumors and the importance of a multidisciplinary approach. The findings contribute to the understanding of the long-term consequences and holistic lifelong care of pediatric patients with suprasellar germinomas.