Case Report
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Apr 6, 2024; 12(10): 1799-1803
Published online Apr 6, 2024. doi: 10.12998/wjcc.v12.i10.1799
Subdural effusion associated with COVID-19 encephalopathy: A case report
Zhi-Yuan Xue, Zhong-Lin Xiao, Ming Cheng, Tao Xiang, Xiao-Li Wu, Qiao-Ling Ai, Yang-Ling Wu, Tao Yang
Zhi-Yuan Xue, Ming Cheng, Tao Xiang, Xiao-Li Wu, Qiao-Ling Ai, Yang-Ling Wu, Tao Yang, Department of Rehabilitation Medicine, Chengdu Jinniu District People’s Hospital, Chengdu 610000, Sichuan Province, China
Zhong-Lin Xiao, Department of Rehabilitation Medicine, The General Hospital of the Western Theater Command of the People’s Liberation Army of China, Chengdu 610000, Sichuan Province, China
Author contributions: All authors made a significant contribution to the work reported, whether that was in the conception, study design, execution, acquisition of data, analysis and interpretation, or in all these areas; all authors took part in drafting, revising, or critically reviewing the article; gave final approval of the version to be published; have agreed on the journal to which the article has been submitted; and agree to be accountable for all aspects of the work.
Informed consent statement: The study participant provided written informed consent before enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Ming Cheng, MD, PhD, Director, Department of Rehabilitation Medicine, Chengdu Jinniu District People’s Hospital, No. 389 Huazhaobi Road, Jinniu District, Chengdu 610000, Sichuan Province, China.
Received: November 16, 2023
Peer-review started: November 16, 2023
First decision: December 26, 2023
Revised: January 7, 2024
Accepted: March 8, 2024
Article in press: March 8, 2024
Published online: April 6, 2024
Core Tip

Core Tip: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may transmit via the retrograde axonal pathway, bloodstream, or direct penetration through the blood-brain barrier, exerting its effects on angiotensin-converting enzyme-2 receptors. This intricate interaction can cause neurological complications, including subdural effusion, which is very rare. Clinical vigilance is advised for cranial imaging in individuals with SARS-CoV-2 infection to enhance diagnostic precision. Considering its unique characteristics, subdural effusion, a seldom reported complication, warrants attention.