Systematic Reviews
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Dec 16, 2022; 10(35): 12946-12958
Published online Dec 16, 2022. doi: 10.12998/wjcc.v10.i35.12946
De novo non-alcoholic fatty liver disease after pancreatectomy: A systematic review
Parth Shah, Vanisha Patel, Motaz Ashkar
Parth Shah, Motaz Ashkar, Gastroenterology, Washington University in Saint Louis, Saint Louis, MO 63110, United States
Vanisha Patel, Internal Medicine, Washington University in Saint Louis, Saint Louis, MO 63110, United States
Author contributions: All authors participated in gathering articles, synthesizing data, and writing the paper.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRSIAM 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Motaz Ashkar, MBBS, MS, Assistant Professor, Staff Physician, Gastroenterology, Washington University in Saint Louis, 660 S. Euclid Avenue, Saint Louis, MO 63110, United States. motaz.ashkar@wustl.edu
Received: August 24, 2022
Peer-review started: August 24, 2022
First decision: September 25, 2022
Revised: October 10, 2022
Accepted: November 22, 2022
Article in press: November 22, 2022
Published online: December 16, 2022
Core Tip

Core Tip: As surgical techniques for pancreatectomy have improved, patients have had an improvement in mortality which has allowed further investigation into the metabolic changes after surgery. Currently there are no guidelines on the management or prevention of de novo non-alcoholic fatty liver disease (NAFLD) after pancreatectomy. In this review, we synthesize both the patterns and risk factors of de novo NAFLD to help guide management.