Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jun 26, 2022; 10(18): 6333-6337
Published online Jun 26, 2022. doi: 10.12998/wjcc.v10.i18.6333
Creutzfeldt-Jakob disease presenting with bilateral hearing loss: A case report
Seunghee Na, Se A Lee, Jong Dae Lee, Eek-Sung Lee, Tae-Kyeong Lee
Seunghee Na, Department of Neurology, Incheon St. Mary’s Hospital, The Catholic University of Korea, Incheon 21431, South Korea
Se A Lee, Jong Dae Lee, Department of Otorhinolaryngology-Head and Neck Surgery, Soonchunhyang University Bucheon Hospital, Bucheon 14584, South Korea
Eek-Sung Lee, Tae-Kyeong Lee, Department of Neurology, Soonchunhyang University Bucheon Hospital, Bucheon 14584, South Korea
Author contributions: Lee ES conceived and designed the study; Lee TK provided supervision; Lee ES and Lee collected the data; Lee SN wrote the first draft of the manuscript; Lee SA and Lee JD edited and contributed to critical revision; and All authors read and approved the final version of the manuscript for submission.
Supported by National Research Foundation of Korea, No. 2019R1C1C1006539.
Informed consent statement: The authors declare that this single case report has been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Eek-Sung Lee, MD, PhD, Assistant Professor, Department of Neurology, Soonchunhyang University Bucheon Hospital, 170, Jomaru-ro, Bucheon 14584, South Korea.
Received: February 9, 2022
Peer-review started: February 9, 2022
First decision: March 23, 2022
Revised: March 24, 2022
Accepted: April 22, 2022
Article in press: April 22, 2022
Published online: June 26, 2022
Core Tip

Core Tip: Hearing impairment as an initial manifestation of Creutzfeldt-Jakob disease is rare. However, it should be regarded as a differential diagnosis in an elderly patient with bilateral hearing impairment unresponsive to standard corticosteroid treatment. Repeat brain imaging including diffusion-weighted imaging and cerebrospinal fluid analysis will be helpful for diagnosis.