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World J Clin Cases. Jul 16, 2013; 1(4): 149-151
Published online Jul 16, 2013. doi: 10.12998/wjcc.v1.i4.149
Published online Jul 16, 2013. doi: 10.12998/wjcc.v1.i4.149
Vulvar granular cell tumor
Michel E Rivlin, G Rodney Meeks, Mohamed A Ghafar, Jack R Lewin, Departments of Obstetrics, Gynecology and Pathology, University of Mississippi Medical Center, Jackson, MS 39216, United States
Author contributions: Rivlin ME, Meeks GR, Ghafar MA and Lewin JR contributed equally to the manuscript.
Correspondence to: Michel E Rivlin, MD, Department of Obstetrics and Gynecology, University of Mississippi Medical Center, 2500 N State Str., Jackson, MS 39216, United States. mrivlin@umc.edu
Telephone: +1-601-9845314 Fax: +1-601-9845477
Received: April 19, 2013
Revised: May 31, 2013
Accepted: June 8, 2013
Published online: July 16, 2013
Revised: May 31, 2013
Accepted: June 8, 2013
Published online: July 16, 2013
Core Tip
Core tip: Granular cell tumors are rare, usually benign, soft tissue tumors of neural origin. They can occur anywhere in the body with up to 15% situated in the vulva. Malignancy has been reported in about 2% of cases. We report a woman with a granular cell tumor of the vulva who underwent tumor excision but with focal extension to the resection margin on microscopy. Recurrence rates are 2%-8% with clear margins and 20% with positive margins. We conclude that intraoperative assessment by frozen section is advisable such that further excision can be performed for positive margins.