Published online Nov 6, 2019. doi: 10.12998/wjcc.v7.i21.3446
Peer-review started: July 12, 2019
First decision: August 2, 2019
Revised: August 10, 2019
Accepted: September 13, 2019
Article in press: September 13, 2019
Published online: November 6, 2019
Compared with organic gastroenteropathy, irritable bowel syndrome (IBS) is more prone to cognitive bias and emotional disorders, which can lead to "abnormal" psychological behavior patterns. IBS can affect the nervous system function of patients through hypothalamus-pituitary-adrenal axis and so on, cause increased vagus nerve excitability, stimulate intestinal peristalsis and mucosal gland secretion, and cannot relieve gastrointestinal symptoms. Therefore, it is very important to correct patients' cognitive biases and coping styles for the fundamental treatment of diseases.
Studies have confirmed that IBS patients generally have cognitive biases and negative coping styles, accompanied by negative emotions. Clinically, the improvement of symptoms is often limited to drugs or single CBT therapy. However, if the treatment strategy of combining mental psychology and body cannot be adopted in a way of both body and mind, it is difficult to realize the integrated regulation of brain-intestine axis, and the disease cannot be fundamentally solved. According to some research reports, exercise can improve the mood of IBS patients. Therefore, on the basis of cognitive behavioral therapy, exercise therapy is used as an auxiliary therapy to correct the cognitive bias of patients and produce positive coping styles, which may be an important strategy for rehabilitation treatment of IBS.
The research objective of this study was to explore the effect of cognitive behavioral therapy combined with exercise intervention on cognitive bias and coping styles of patients with diarrhea-predominant IBS to provide a theoretical reference for the prevention and treatment of diarrhea-predominant IBS.
We retrospectively analyzed 60 patients with diarrhea-predominant IBS aged 30-40 years and 30 healthy subjects recruited from January 2018 to October 2018. They were randomly divided into the experimental group and the control group. All subjects received 24 wk of continuous intervention program. Statistical analysis was conducted through repeated measurement variance analysis, and correlation and regression analysis were used to determine correlation.
Our study found that patients with IBS have obvious cognitive bias and negative coping styles compared with normal people. IBS-SSS symptom score is significantly correlated with ATQ, DAS and CSQ scores.
Cognitive behavioral therapy combined with exercise intervention can well correct the cognitive bias of diarrhea IBS patients and eliminate the adverse coping conditions of patients, which is of great significance for the treatment of IBS and psychosomatic diseases.
The number of subjects included in our study is relatively small, the intervention time is relatively short, and there are not enough observation indicators to more fully reflect the clinical situation of patients. In future research, more attention should be paid to the above deficiencies.